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6750-60-3

6750-60-3 structure
6750-60-3 structure
  • Name: Spathulenol
  • Chemical Name: (1aR,4aR,7S,7aR,7bR)-1,1,7-Trimethyl-4-methylenedecahydro-1H-cycl opropa[e]azulen-7-ol
  • CAS Number: 6750-60-3
  • Molecular Formula: C15H24O
  • Molecular Weight: 220.350
  • Catalog: Natural product Sesquiter
  • Create Date: 2017-06-22 15:36:26
  • Modify Date: 2025-08-20 17:45:26
  • Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].

Name (1aR,4aR,7S,7aR,7bR)-1,1,7-Trimethyl-4-methylenedecahydro-1H-cycl opropa[e]azulen-7-ol
Synonyms spathulenol
(1aR,4aR,7S,7aR,7bR)-1,1,7-Trimethyl-4-methylenedecahydro-1H-cyclopropa[e]azulen-7-ol
1H-Cycloprop[e]azulen-7-ol, decahydro-1,1,7-trimethyl-4-methylene-, (1aR,4aR,7S,7aR,7bR)-
Espatulenol
10'-Apocarotenal
Description Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system[1].
Related Catalog
In Vitro Spathulenol exhibits a high antioxidant activity s in the DPPH and MDA system, exhibits significant DPPH free radical activity, with IC50 values of 85.60 μg/mL[1].
In Vivo Spathulenol (oral administration; 300 mg/kg) shows a significant inhibition in the Cg-induced mice paw oedema and pleurisy model[1]. In a spontaneous lipoperoxidation rat brain homogenate model, when incubated in controlled temperature andoxygenation conditions, PG-1 exhibits a high activity with an IC50 value of 26.13 μg/mL, respectively, which iscomparable to a commercial antioxidant BHT (38.41 μg/mL), Thus, PG-1 contributes to a decrease in the generation of MDA,which is a toxic product resulting from the degradation of the cell membrane by lipid peroxidation, causing cell ruptures and mutations[1].
References

[1]. Nascimento KF, et al. Antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities of the essential oil of Psidium guineense Sw. and spathulenol.J Ethnopharmacol. 2018 Jan 10;210:351-358.

Density 1.0±0.1 g/cm3
Boiling Point 297.0±19.0 °C at 760 mmHg
Molecular Formula C15H24O
Molecular Weight 220.350
Flash Point 123.9±13.7 °C
Exact Mass 220.182709
PSA 20.23000
LogP 4.45
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.528
Hazard Codes Xi
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