956136-95-1
956136-95-1 structure
- Name: LCQ-908
- Chemical Name: 2-[4-[4-[5-[[6-(trifluoromethyl)pyridin-3-yl]amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid
- CAS Number: 956136-95-1
- Molecular Formula: C25H24F3N3O2
- Molecular Weight: 455.472
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acyltransferase
- Create Date: 2017-08-22 12:02:41
- Modify Date: 2024-01-05 22:40:56
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Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor.
| Name | 2-[4-[4-[5-[[6-(trifluoromethyl)pyridin-3-yl]amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid |
|---|---|
| Synonyms |
Pradigastat [INN]
{trans-4-[4-(5-{[6-(Trifluoromethyl)-3-pyridinyl]amino}-2-pyridinyl)phenyl]cyclohexyl}acetic acid Cyclohexaneacetic acid, 4-[4-[5-[[6-(trifluoromethyl)-3-pyridinyl]amino]-2-pyridinyl]phenyl]-, trans- LCQ 908 Pradigastat LCQ 908NXA UNII-2U23G6VNUZ LCQ908-NXA LCQ-908 |
| Description | Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor. |
|---|---|
| Related Catalog | |
| In Vivo | Pradigastat (LCQ-908) is a potent inhibitor of DGAT1, and has been used for the phase II clinical trials to treat diabetes and obesity[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 611.0±55.0 °C at 760 mmHg |
| Molecular Formula | C25H24F3N3O2 |
| Molecular Weight | 455.472 |
| Flash Point | 323.3±31.5 °C |
| Exact Mass | 455.182068 |
| PSA | 75.11000 |
| LogP | 6.10 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.582 |
| Storage condition | 2-8℃ |