LCQ-908
Modify Date: 2025-08-22 20:49:07
LCQ-908 structure
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Common Name | LCQ-908 | ||
|---|---|---|---|---|
| CAS Number | 956136-95-1 | Molecular Weight | 455.472 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 611.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C25H24F3N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 323.3±31.5 °C | |
Use of LCQ-908Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor. |
| Name | 2-[4-[4-[5-[[6-(trifluoromethyl)pyridin-3-yl]amino]pyridin-2-yl]phenyl]cyclohexyl]acetic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Pradigastat (LCQ-908) is a diacylglycerol acyltransferase 1 (DGAT1) inhibitor. |
|---|---|
| Related Catalog | |
| In Vivo | Pradigastat (LCQ-908) is a potent inhibitor of DGAT1, and has been used for the phase II clinical trials to treat diabetes and obesity[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 611.0±55.0 °C at 760 mmHg |
| Molecular Formula | C25H24F3N3O2 |
| Molecular Weight | 455.472 |
| Flash Point | 323.3±31.5 °C |
| Exact Mass | 455.182068 |
| PSA | 75.11000 |
| LogP | 6.10 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.582 |
| InChIKey | GXALXAKNHIROPE-UHFFFAOYSA-N |
| SMILES | O=C(O)CC1CCC(c2ccc(-c3ccc(Nc4ccc(C(F)(F)F)nc4)cn3)cc2)CC1 |
| Storage condition | 2-8℃ |
| Pradigastat [INN] |
| {trans-4-[4-(5-{[6-(Trifluoromethyl)-3-pyridinyl]amino}-2-pyridinyl)phenyl]cyclohexyl}acetic acid |
| Cyclohexaneacetic acid, 4-[4-[5-[[6-(trifluoromethyl)-3-pyridinyl]amino]-2-pyridinyl]phenyl]-, trans- |
| LCQ 908 |
| Pradigastat |
| LCQ 908NXA |
| UNII-2U23G6VNUZ |
| LCQ908-NXA |
| LCQ-908 |