3705-26-8
3705-26-8 structure
- Name: Cyclo(L-Phe-L-Pro)
- Chemical Name: cyclo(-phe-pro)
- CAS Number: 3705-26-8
- Molecular Formula: C14H16N2O2
- Molecular Weight: 244.289
- Catalog: Natural product Alkaloid
- Create Date: 2018-10-04 08:07:26
- Modify Date: 2025-08-26 20:26:47
-
Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3].
| Name | cyclo(-phe-pro) |
|---|---|
| Synonyms |
CYCLO-L-PHENYLALANYL-L-PROLINE
(3S,8aS)-3-Benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione (3S-trans)-3-Benzylhexahydropyrrolo(1,2-a)pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)-, (3S,8aS)- Einecs 223-047-0 |
| Description | Cyclo(L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo(L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo(L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 509.5±39.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.289 |
| Flash Point | 262.0±27.1 °C |
| Exact Mass | 244.121185 |
| PSA | 49.41000 |
| LogP | -0.56 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.614 |
| Storage condition | -15°C |
| Hazard Codes | Xi |
|---|