491-60-1

491-60-1 structure

Name: Emodinanthrone
Chemical Name: 1,3,8-trihydroxy-6-methyl-10H-anthracen-9-one
CAS Number: 491-60-1
Molecular Formula: C₁₅H₁₂O₄
Molecular Weight: 256.25300
Catalog: Research Areas Infection
Create Date: 2018-05-07 08:00:00
Modify Date: 2024-01-03 18:31:56
Emodinanthrone, an anthraquinone, is a sprecursor of Emodin with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli[1][2][3].

Name	1,3,8-trihydroxy-6-methyl-10H-anthracen-9-one
Synonyms	1,3,8-Trihydroxy-6-methyl-anthron 6-methyl-1,3,8-trihydroxy-10H-anthracene-9-one Emodinanthrone 1,3,8-trihydroxy-6-methyl-anthrone

Description	Emodinanthrone, an anthraquinone, is a sprecursor of Emodin with antibiotic activity. Emodinanthrone inhibits respiration-driven solute transport at micromolar concentrations in membrane vesicles of Escherichia coli[1][2][3].
Related Catalog	Research Areas >> Infection
In Vitro	Emodinanthrone is used as an alternative substrate for the AknX oxygenase assay[1].
References	[1]. Jin-Young Chung, et al. Expression, purification, and characterization of AknX anthrone oxygenase, which is involved in aklavinone biosynthesis in Streptomyces galilaeus. J Bacteriol. 2002 Nov;184(22):6115-22. [2]. T Ubbink-Kok, et al. Inhibition of electron transfer and uncoupling effects by emodin and emodinanthrone in Escherichia coli. Antimicrob Agents Chemother. 1986 Jul;30(1):147-51. [3]. M K Wang, et al. Triterpenoid saponins from Berneuxia thebetica. Phytochemistry. 1998 Aug;48(8):1411-4.

Density	1.471 g/cm3
Boiling Point	556.2ºC at 760 mmHg
Melting Point	254-258 °C(dec.)
Molecular Formula	C₁₅H₁₂O₄
Molecular Weight	256.25300
Exact Mass	256.07400
PSA	77.76000
LogP	2.24700
Vapour Pressure	5.6E-13mmHg at 25°C
Index of Refraction	1.723

Hazard Codes	Xi

518-82-1

~96%

491-60-1

Literature: HY BIOPHARMA, INC.; TOBIA, Alfonso, J.; CABANA, Bernard, E.; VADLAPATLA, Venkata; CONNOLLY, Ronald, H. Patent: WO2011/34922 A1, 2011 ; Location in patent: Page/Page column 9 ;

33770-95-5

~87%

491-60-1

Literature: Liang, Jing Lu; Cha, Hyo Chang; Lee, Seung Ho; Son, Jong-Keun; Chang, Hyeun Wook; Eom, Ji-Eun; Kwon, Youngjoo; Jahng, Yurngdong Archives of Pharmacal Research, 2012 , vol. 35, # 3 p. 447 - 454

6030-60-0

491-60-1

1373404-37-5

491-60-1

481-73-2

491-60-1

Literature: Anslow; Breen; Raistrick Biochemical Journal, 1940 , vol. 34, p. 159,165

517-48-6

491-60-1

Literature: Oxford; Raistrick Biochemical Journal, 1940 , vol. 34, p. 790,799

481-73-2

10034-85-2

64-19-7

491-60-1

Literature: Anslow; Breen; Raistrick Biochemical Journal, 1940 , vol. 34, p. 159,165

21871-90-9

10034-85-2

108-24-7

491-60-1

Literature: Eder Archiv der Pharmazie (Weinheim, Germany), 1915 , vol. 253, p. 32 Archiv der Pharmazie (Weinheim, Germany), 1916 , vol. 254, p. 18,30 Full Text Show Details Tutin; Clewer Journal of the Chemical Society, 1912 , vol. 101, p. 294

96822-98-9

491-60-1

Precursor 7
518-82-1 33770-95-5 6030-60-0 481-73-2
10034-85-2 64-19-7 21871-90-9
DownStream 5
548-03-8 518-82-1 491-58-7 61281-22-9
61281-23-0

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