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132-60-5

132-60-5 structure

132-60-5 structure

Name: Cinchophen
Chemical Name: 2-Phenylquinoline-4-carboxylic Acid
CAS Number: 132-60-5
Molecular Formula: C₁₆H₁₁NO₂
Molecular Weight: 249.264
Catalog: API Antipyretic analgesics Non-steroidal anti-inflammatory drugs
Create Date: 2018-08-19 17:17:12
Modify Date: 2026-07-17 00:23:46
Cinchophen is an effective method for producing chronic peptic ulcer in dogs.

Name	2-Phenylquinoline-4-carboxylic Acid
Synonyms	RHEMATAN quinofen PHENYLCINCHONINIC ACID ikterosan 2-PHENYLCINCHONINIC ACID EINECS 205-067-1 CINCHOPHENE 2-Phenyl-4-quinolinecboxylic acid tophol 2-phenylquinoline-4-carboxylic acid RHEUMIN agotan texin aminophan tam Cinchophen~2-Phenylcinchoninic acid 2-Phenylcinchoninic acid, Cinchophen aciphenochinolinium tophosan atophane tervalon cinchophenicacid polyphlogin atocin MFCD00006750 2-PHENYLQUINOLEINE-4-CBOXYLIC ACID 2-Phenylquinoline-4-caboxylic acid alutyl 2-phenylquinoline-4-cboxlicacid 2-phenyl-cinchoninicaci acifenokinolin atigoa cinconal MYLOFANOL atophan LABOTEST-BB LT00453769 SALOR-INT L163163-1EA PHENOQUIN 2-Phenyl-4-quinolinecarboxylic acid cincophen tamin phenophan 2-Phenylcinchoninic Acid AURORA KA-7375 Cinchopen 2-Phenyl-4-quinolinecboxylic acid, R 2-PHENYLQUINOLINE-4-CBOXYLIC ACID viophan QUINOPHAN vantyl 2-phenylcinchonicacid ASISCHEM T80817 atofan aciphenochinoline TIMTEC-BB SBB000885 traubofan cincosal quinophen CINCHOPHEN 2-phenyl-4-quinolinecboxylicaci

Description	Cinchophen is an effective method for producing chronic peptic ulcer in dogs.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology

Density	1.3±0.1 g/cm3
Boiling Point	456.9±33.0 °C at 760 mmHg
Melting Point	213-216ºC
Molecular Formula	C₁₆H₁₁NO₂
Molecular Weight	249.264
Flash Point	230.1±25.4 °C
Exact Mass	249.078979
PSA	50.19000
LogP	3.99
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.682
Storage condition	Store below +30°C.
Water Solubility	alcohol: soluble1g in 120ml(lit.) \| Insoluble in water

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD4025000

CHEMICAL NAME :: Cinchoninic acid, 2-phenyl-

CAS REGISTRY NUMBER :: 132-60-5

BEILSTEIN REFERENCE NO. :: 0192803

LAST UPDATED :: 199612

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C16-H11-N-O2

MOLECULAR WEIGHT :: 249.28

WISWESSER LINE NOTATION :: T66 BNJ CR& EVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human

DOSE/DURATION :: 214 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,177,1969

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Human - man

DOSE/DURATION :: 74 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85DCAI "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970 Volume(issue)/page/year: 2,73,1970

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: LDTU** "Narkoseversuche mit Hoheren Alkoholen und Stickstoffderivaten, Dissertation," Leube, F., Pharmakologischen Institut der Universitat Tubingen, Fed. Rep. Ger., 1931 Volume(issue)/page/year: -,-,1931

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD691-490

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 74,365,1942 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2800 mg/kg/7D-I

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 48,341,1933

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S24/25
RIDADR	UN 3249
WGK Germany	3
RTECS	GD4025000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933499090

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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