Antipyretic analgesics

Antipyretic and analgesic drugs are a class of drugs that have antipyretic and analgesic effects and most have anti-inflammatory and anti-rheumatic effects. It mainly produces antipyretic, analgesic and anti-inflammatory effects by inhibiting the synthesis of prostaglandins in the central nervous system and peripheral tissues, and only relieves moderate to moderate pain for analgesic effects. Fever is a kind of defense reaction of the child's body itself, but it is unfavorable to the child's body when it is hot, such as causing febrile seizures and life-threatening in severe cases. Prompt use of antipyretic analgesics can reduce body temperature, improve symptoms, and prevent convulsions such as convulsions. However, it should be noted that sudden drop in body temperature and excessive sweating may cause collapse. Therefore, you should not take too much medicine and drink more water after taking the medicine. Children with a history of high heat convulsions can be combined with the sedative drug luminal, and taking paracetamol tablets early in the fever can prevent febrile seizures. According to the chemical structure, it is divided into four categories: 1. Aniline. Such as phenacetin, acetaminophen and so on. 2. Pyrazolones. Such as aminopyrine, Analgin, Baotaisong and so on. 3. Salicylic acid. Such as aspirin, sodium salicylate. 4. New anti-inflammatory analgesics. Such as indomethacin, mefenamic acid, ibuprofen and ibuprofen, and iloprofen. This class of drugs has a common adverse reaction, such as a small number of patients can have rash, leukopenia, angioedema, anaphylactic shock and so on. Large doses can cause gastrointestinal reactions and liver and kidney dysfunction. Aspirin has a stimulating effect on the gastrointestinal tract. Long-term use can cause gastritis, gastric ulcer and hemorrhage, which can induce bronchial asthma and Reye's syndrome, which are characterized by convulsions and liver damage. In addition to general adverse reactions, An Nai has occasional severe leukopenia, exfoliative dermatitis and drug fever. Paracetamol has fewer adverse reactions, is non-irritating to the stomach, does not cause stomach bleeding, and occasionally has an allergic reaction such as rash. Long-term use of large amounts may have liver and kidney dysfunction. Side effects such as phenacetin and aminopyrine are relatively heavy, so as little as possible compound aspirin (APC) drugs. There is currently a trend to promote paracetamol and a small amount of water-soluble aspirin alone.