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87075-18-1

87075-18-1 structure
87075-18-1 structure
  • Name: Isolindleyin
  • Chemical Name: Isolindleyin
  • CAS Number: 87075-18-1
  • Molecular Formula: C23H26O11
  • Molecular Weight: 478.44600
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Tyrosinase
  • Create Date: 2018-08-16 13:06:46
  • Modify Date: 2024-01-05 19:20:15
  • Isolindleyin, a butyrophenone, is a tyrosinase inhibitor, with a Kd of 54.8 μM for human tyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1].

Name Isolindleyin
Synonyms 4-(4'-hydroxyphenyl)-2-butanone 4'-O-β-D-(2-O-galloyl)-glycopyranoside
Description Isolindleyin, a butyrophenone, is a tyrosinase inhibitor, with a Kd of 54.8 μM for human tyrosinase. Isolindleyin exhibits anti-inflammatory, analgesic and anti-melanogenic activities[1].
Related Catalog
Target

Kd: 54.8 μM (human tyrosinase)[1]

In Vitro Isolindley (1-500 μM; 7 days) suppresses melanin synthesis in human epidermal melanocytes[1].
References

[1]. Lee JY, et, al. Isolindleyin exerts anti-melanogenic effects in human epidermal melanocytes via direct binding to tyrosinase. Biochem Biophys Res Commun. 2021 Jan 1;534:802-807.

Molecular Formula C23H26O11
Molecular Weight 478.44600
Exact Mass 478.14800
PSA 183.21000
LogP 0.36840
Precursor  0

DownStream  1