19771-63-2

19771-63-2 structure

Name: Oxothiazolidinecarboxylic acid
Chemical Name: (4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
CAS Number: 19771-63-2
Molecular Formula: C₄H₅NO₃S
Molecular Weight: 147.152
Catalog: Biochemical Common amino acids and protein drugs
Create Date: 2018-07-09 19:50:20
Modify Date: 2024-01-02 14:47:47
Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis[1].

Name	(4R)-2-oxo-1,3-thiazolidine-4-carboxylic acid
Synonyms	L-2-Oxothiazolidine-4-carboxylic Acid 2-oxothiazolidine-4(R)-carboxylic acid 4-Thiazolidinecarboxylic acid, 2-oxo-, (4R)- 4-Thiazolidinecarboxylic acid,2-oxo-,(R)-[] OTCA L-2-Oxothiazolidine-4-carboxylate (4R)-2-Oxothiazolidine-4-carboxylic acid (R)-(−)-2-Oxothiazolidine-4-carboxylic acid L-(−)-2-Oxothiazolidine-4-carboxylic acid L-2-Oxo-4-thiazolidinecarboxylic acid (R)-2-oxothiazolidine-4-carboxylic acid L-(−)-2-Oxothiazolidine-4-carboxylic acid (4R)-2-Oxo-1,3-thiazolidine-4-carboxylic acid (−)-2-Oxo-4-thiazolidinecarboxylic acid MFCD00066092 Procysteine Oxothiazolidine carboxylate,L (4R)-2-oxo-4-thiazolidine-carboxylic acid 4-Thiazolecarboxylic acid, 4,5-dihydro-2-hydroxy-, (4R)- (4R)-2-Hydroxy-4,5-dihydro-1,3-thiazole-4-carboxylic acid L-2-Thiazolidinone-4-carboxylic Acid 2-Oxothiazolidine-4-carboxylate,L (R)-(−)-2-Oxothiazolidine-4-carboxylic acid

Description	Oxothiazolidinecarboxylic acid, an antioxidant, is a prodrug of cysteine that is inert until metabolized to cysteine intracellulary, thus stimulating glutathione synthesis[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
In Vivo	Oxothiazolidinecarboxylic acid treatment attenuates plantaris atrophy, restored glutathione levels, and increased catalase, Cu/Zn-SOD1, and Mn-SOD2 mRNA expression, but did not reduce other markers of oxidant stress or levels of these catabolic factors[1]. Animal Model: Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group)[1]. Dosage: 0.35% (w/v). Administration: Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk. Result: Increased fiber CSAs compared to the non-supplemented, alcohol-fed group.
References	[1]. Jeffrey S Otis, et al. Procysteine Stimulates Expression of Key Anabolic Factors and Reduces Plantaris Atrophy in Alcohol-Fed Rats. Alcohol Clin Exp Res. 2009 Aug;33(8):1450-9.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,109,1993

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,164,1992

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,164,1992

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi: Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XJ5426650
HS Code	2934999090