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52-90-4

52-90-4 structure
52-90-4 structure
Name L-cysteine
Synonyms H-CYS-OH
(S)-(-)-Cysteine
L-Cysteine - non-animal origin
L(+)-CYSTEINE BIOSYNTH
L-CYSTEINE, S-BENZYL
l-2-amino-3-mercaptopropionic acid
E 920
half-cysteine
Acetylcysteine Impurity 2（Acetylcysteine Impurity B）
(2R)-2-Amino-3-sulphanylpropanoic acid, (2R)-2-Amino-3-mercaptopropionic acid, (2R)-2-Amino-3-mercaptopropanoic acid
Cysteine (C)
3-mercapto-l-alanin
(R)-(+)-CYSTEINE
alpha-amino-beta-thiolpropionicacid
b-Mercaptoalanine
Cys
cystein
L-CysteineForBiochemistry-(R)-3-Amino-3-MercaptopropionicAcid)
BETA-MERCAPTO-L-ALANINE
(R)-(+)-Cysteine
Acetylcysteine Impurity B
L-CYSTEINE
FEMA 3263
L-β-Mercaptoalanine
Acetylcysteine Impurity B (L-Cysteine)
Acetylcysteine Impurity B-13C3
Thioserine
(+)-2-Amino-3-mercaptopropionic acid
Acetylcysteine Impurity 2
Cystein
L-Cysteine,(R)-2-Amino-3-mercaptopropionic acid
(2R)-2-amino-3-sulfanylpropanoic acid
(R)-2-AMINO-3-MERCAPTOPROPIONIC ACID
hydrogen L-cysteinate
(R)-2-Amino-3-mercaptopropionic acid
MFCD00064306
L-CYSTEINE, PHMA
Cysteine
CYSTEINE, L-(P)
H-Cys-OH.Hcl
L-(+)-CYSTEINE
alpha-Amino-beta-thiolpropionic acid
alpha-amino-beta-mercaptopropionicacid
L-Cysteine-1-13C
Cysteine (C) Solution, 100ppm
CYTISINE(LABURNIN)(RG)
H-Cys-OH
The L- cysteine
L(+)-CYSTEIN
L-2-Amino-3-mercaptopropionic acid
CYSH
L-Cysteine
3-mercapto-L-Alanine
L-Cys
Cysteine Solution (C)
a-Amino-b-thiolpropionic Acid
L-CYSTEINUM
(R)-2-Amino-3-mercaptopropanoic acid
L-CYSTEINE FREE BASE, BIOTECHNOLOGY &
CYSTEINE, L
EINECS 200-158-2
CYSTEINE
3-Mercapto-L-alanine
L-Cysteine 0.1 M solution
L-2-AMINO-3-MERCAPTOPROPANOIC ACID
(2R)-2-amino-3-sulfanyl-propanoic acid
L-beta-Mercaptoalanine
(R)-2-amino-3-mercapto-Propanoic acid
L-CYSTEINE FREE BASE CRYSTALLINE
(2R)-2-amino-3-mercaptopropanoic acid
L-CYSTEINE (2,3,3-D3, )
L-CysteineForBiochemistry
L-Cysteine, R
L-Cysteine - animal origin
(R)-Cysteine
Description L-Cysteine is a thiol-containing non-essential amino acid that is oxidized to form cystine.
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. McGavigan AK, et al. L-cysteine suppresses ghrelin and reduces appetite in rodents and humans. Int J Obes (Lond). 2015 Mar;39(3):447-55.
Density 1.3±0.1 g/cm3
Boiling Point 293.9±35.0 °C at 760 mmHg
Melting Point 220 °C (dec.)(lit.)
Molecular Formula C3H7NO2S
Molecular Weight 121.158
Flash Point 131.5±25.9 °C
Exact Mass 121.019745
PSA 102.12000
LogP 0.23
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.550
Water Solubility 280 g/L (25 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA1600000
CHEMICAL NAME :
Cysteine, L-
CAS REGISTRY NUMBER :
52-90-4
LAST UPDATED :
199710
DATA ITEMS CITED :
31
MOLECULAR FORMULA :
C3-H7-N-O2-S
MOLECULAR WEIGHT :
121.17
WISWESSER LINE NOTATION :
QVYZ1SH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1890 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Kidney, Ureter, Bladder - other changes in urine composition
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1620 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1550 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
660 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1360 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
150 gm/kg/30D-C
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - muscle weakness Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
308 gm/kg/26W-I
TOXIC EFFECTS :
Cardiac - other changes Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
90 gm/kg/30D-C
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - other changes Endocrine - other changes Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
100 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
3600 mg/kg
SEX/DURATION :
female 7-12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Newborn - physical
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
27600 mg/kg
SEX/DURATION :
female 23 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
6 gm/kg
SEX/DURATION :
male 30 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
100 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 68,351,1979 *** REVIEWS *** TOXICOLOGY REVIEW DPIRDU Dangerous Properties of Industrial Materials Report. (Van Nostrand Reinhold, 115 Fifth Ave., New York, NY 10003) V.1- 1981- Volume(issue)/page/year: 3(1),14,1983 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4773 No. of Facilities: 81 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 8402 (estimated) No. of Female Employees: 7734 (estimated)
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful
Risk Phrases R22;R36/37/38
Safety Phrases S36-S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS HA1600000
HS Code 2930901000
HS Code 2930909090
Summary 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%
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