Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Clofazimine
Price:
Purity: 98.0%
Stocking Period: 10 Day
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Clofazimine
Price: ￥1248.0/5g ￥208.0/1g
Purity: 98.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: Clofazimine
Price: ￥Inquiry/1g
Purity: 98.9%
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DC Chemicals Limited
China
Product Name: Clofazimine
Price: $300.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Clofazimine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Contact: Ms Wang

2030-63-9

2030-63-9 structure

2030-63-9 structure

Name: Clofazimine
Chemical Name: clofazimine
CAS Number: 2030-63-9
Molecular Formula: C₂₇H₂₂Cl₂N₄
Molecular Weight: 473.396
Catalog: API Synthetic anti-infective drugs Anti-tuberculosis leprosy
Create Date: 2018-08-21 12:57:38
Modify Date: 2024-01-02 20:24:25
Clofazimine is a fat-soluble iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial drugs to treat AIDS and Crohn's disease.

Name	clofazimine
Synonyms	2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]- N,5-Bis(4-chlorophenyl)-3-(isopropylimino)-3,5-dihydro-2-phenazinamine Clofaziminum [INN-Latin] 2-Phenazinamine, N,5-bis(4-chlorophenyl)-3,5-dihydro-3-((1-methylethyl)imino)- Clofazimine Clofaziminum N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine Chlofazimine Clofazimine (N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine Clofazimina [INN-Spanish] Lamprene Lampren 2-(4-chloro-anilino)-5-(4-chloro-phenyl)-3-isopropylamino-phenazinium-betaine 2-(4-Chlor-anilino)-5-(4-chlor-phenyl)-3-isopropylamino-phenazinium-betain B 663 (Pharmaceutical) N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine Clofazimina

Description	Clofazimine is a fat-soluble iminophenazine dye, has a marked anti-inflammatory effect, has been used in combination with other antimycobacterial drugs to treat AIDS and Crohn's disease.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Dye Reagents Research Areas >> Inflammation/Immunology

Density	1.3±0.1 g/cm3
Boiling Point	566.9±50.0 °C at 760 mmHg
Melting Point	210-212°
Molecular Formula	C₂₇H₂₂Cl₂N₄
Molecular Weight	473.396
Flash Point	296.7±30.1 °C
Exact Mass	472.122162
PSA	42.21000
LogP	7.26
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.667
Water Solubility	Practically insoluble in water, soluble in methylene chloride, very slightly soluble in ethanol (96 per cent). It shows polymorphism (5.9).

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SG1578000

CHEMICAL NAME :: Phenazine, 2,10-dihydro-3-(p-chloroanilino)-10-(p-chlorophenyl)- 2-(isopropylimino)-

CAS REGISTRY NUMBER :: 2030-63-9

BEILSTEIN REFERENCE NO. :: 0060420

LAST UPDATED :: 199612

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C27-H22-Cl2-N4

MOLECULAR WEIGHT :: 473.43

WISWESSER LINE NOTATION :: T C666 BN IN EHJ BR DG& ENUY1&1 FMR DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8400 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Gastrointestinal - hypermotility, diarrhea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 4400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Mutation test systems - not otherwise specified

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 32,911,1994

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn:Harmful;
Risk Phrases	R22
Safety Phrases	S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	SG1578000
HS Code	35040000

Precursor 1
84803-71-4
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%