62949-76-2

62949-76-2 structure

Name: Xanthoangelol
Chemical Name: (E)-1-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
CAS Number: 62949-76-2
Molecular Formula: C₂₅H₂₈O₄
Molecular Weight: 392.48700
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-02-19 23:40:31
Modify Date: 2025-08-25 14:06:04
Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity[1][2]. Xanthoangelol and inhibits monoamine oxidases[3]. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[4].

Name	(E)-1-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
Synonyms	Xanthoangelol xanthoangerol 2',4,4'-trihydroxy-3'-geranylchalcone 3-geranyl-2,4,4'-trihydroxychalcone

Description	Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity[1][2]. Xanthoangelol and inhibits monoamine oxidases[3]. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring). 2016 Nov;24(11):2351-2360. [2]. Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1604-5. [3]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40. [4]. Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28(8) 1404-1407 (2005).