Xanthoangelol

Modify Date: 2024-01-13 03:14:52

Xanthoangelol structure	Common Name	Xanthoangelol
	CAS Number	62949-76-2	Molecular Weight	392.48700
	Density	1.165g/cm3	Boiling Point	605.8ºC at 760 mmHg
	Molecular Formula	C₂₅H₂₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	334.2ºC

Use of Xanthoangelol

Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity[1][2]. Xanthoangelol and inhibits monoamine oxidases[3]. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[4].

Name	(E)-1-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-2,4-dihydroxyphenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
Synonym	More Synonyms

Description	Xanthoangelol, extracted from Angelica keiskei, suppresses obesity-induced inflammatory responses. Xanthoangelol possesses antibacterial activity[1][2]. Xanthoangelol and inhibits monoamine oxidases[3]. Xanthoangelol induces apoptosis in neuroblastoma and leukemia cells[4].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Epigenetics >> AMPK Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> PI3K/Akt/mTOR >> AMPK Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring). 2016 Nov;24(11):2351-2360. [2]. Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1604-5. [3]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40. [4]. Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28(8) 1404-1407 (2005).

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Signaling Pathways >> Epigenetics >> AMPK

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> PI3K/Akt/mTOR >> AMPK

Signaling Pathways >> Anti-infection >> Bacterial

References

[1]. Li Y, et al. Xanthoangelol and 4-hydroxyderrcin suppress obesity-induced inflammatory responses. Obesity (Silver Spring). 2016 Nov;24(11):2351-2360.

[2]. Inamori Y, et al. Antibacterial activity of two chalcones, xanthoangelol and 4-hydroxyderricin, isolated from the root of Angelica keiskei KOIDZUMI. Chem Pharm Bull (Tokyo). 1991 Jun;39(6):1604-5.

[3]. Kim JH, et al. Xanthoangelol and 4-Hydroxyderricin Are the Major Active Principles of the Inhibitory Activities against Monoamine Oxidases on Angelica keiskei K. Biomol Ther (Seoul). 2013 May 30;21(3):234-40.

[4]. Keiichi TABATA, et al. Xanthoangelol, a Major Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma and Leukemia Cells. Biol. Pharm. Bull. 28(8) 1404-1407 (2005).

Density	1.165g/cm3
Boiling Point	605.8ºC at 760 mmHg
Molecular Formula	C₂₅H₂₈O₄
Molecular Weight	392.48700
Flash Point	334.2ºC
Exact Mass	392.19900
PSA	77.76000
LogP	5.93470
Index of Refraction	1.625

Xanthoangelol

xanthoangerol

2',4,4'-trihydroxy-3'-geranylchalcone

3-geranyl-2,4,4'-trihydroxychalcone

Xanthoangelol

Use of Xanthoangelol

Names

Xanthoangelol Biological Activity

Chemical & Physical Properties

Synthetic Route

Synonyms