129280-33-7
129280-33-7 structure
- Name: Semilicoisoflavone B
- Chemical Name: semilicoisoflavone B
- CAS Number: 129280-33-7
- Molecular Formula: C20H16O6
- Molecular Weight: 352.337
- Catalog: Natural product Flavonoids
- Create Date: 2017-05-07 20:37:23
- Modify Date: 2024-01-09 17:52:10
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Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].
| Name | semilicoisoflavone B |
|---|---|
| Synonyms |
4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-
SemilicoisoflavoneB 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one 5,7,8'-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one Semilicoisoflavone B |
| Description | Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 615.5±55.0 °C at 760 mmHg |
| Molecular Formula | C20H16O6 |
| Molecular Weight | 352.337 |
| Flash Point | 225.5±25.0 °C |
| Exact Mass | 352.094696 |
| PSA | 100.13000 |
| LogP | 4.48 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.683 |
| Hazard Codes | Xi |
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