Semilicoisoflavone B

Modify Date: 2025-08-25 18:54:16

Semilicoisoflavone B Structure
Semilicoisoflavone B structure
Common Name Semilicoisoflavone B
CAS Number 129280-33-7 Molecular Weight 352.337
Density 1.4±0.1 g/cm3 Boiling Point 615.5±55.0 °C at 760 mmHg
Molecular Formula C20H16O6 Melting Point N/A
MSDS N/A Flash Point 225.5±25.0 °C

 Use of Semilicoisoflavone B


Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].

 Names

Name semilicoisoflavone B
Synonym More Synonyms

 Semilicoisoflavone B Biological Activity

Description Semilicoisoflavone B, an isoflavone, mainly derived from Glycyrrhiza uralensis Fisch.. Semilicoisoflavone B reduces amyloid β (Aβ) secretion by inhibiting β-secretase-1 (BACE1) expression and activity. Semilicoisoflavone B decreases BACE1 expression mainly through increasing PPARγ expression and inhibiting STAT3 phosphorylation[1].
Related Catalog
References

[1]. Gu MY, et al. Glycyrrhiza uralensis and Semilicoisoflavone B Reduce Aβ Secretion by Increasing PPARγ Expression and Inhibiting STAT3 Phosphorylation to Inhibit BACE1 Expression. Mol Nutr Food Res. 2018 Mar;62(6):e1700633.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 615.5±55.0 °C at 760 mmHg
Molecular Formula C20H16O6
Molecular Weight 352.337
Flash Point 225.5±25.0 °C
Exact Mass 352.094696
PSA 100.13000
LogP 4.48
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.683

 Safety Information

Hazard Codes Xi

 Synonyms

4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(8-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-
SemilicoisoflavoneB
5,7-dihydroxy-3-(8-hydroxy-2,2-dimethylchromen-6-yl)chromen-4-one
5,7,8'-Trihydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one
Semilicoisoflavone B
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