2348-77-8

2348-77-8 structure
2348-77-8 structure
  • Name: 1,4-Naphthalenedione,2-phenyl-
  • Chemical Name: 2-phenylnaphthalene-1,4-dione
  • CAS Number: 2348-77-8
  • Molecular Formula: C16H10O2
  • Molecular Weight: 234.25
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2017-11-22 13:54:48
  • Modify Date: 2024-01-10 19:46:41
  • Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL[1].

Name 2-phenylnaphthalene-1,4-dione
Synonyms 1.4-Dioxo-2-phenyl-naphthalin-dihydrid-(1.4)
1,4-Naphthalenedione,2-phenyl
2-phenyl-1,4-naphthalenedione
2-phenyl-[1,4]naphthoquinone
2-Phenyl-[1,4]naphthochinon
1,4-Naphthoquinone,2-phenyl
Description Anti-infective agent 1 (compound 3a) is a potent and selective antiprotozoal and antimycobacterial agent. Anti-infective agent 1 shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 10.95 and 0.06 μM, respectively. Anti-infective agent 1 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 8 μg/mL[1].
Related Catalog
References

[1]. Kalt MM, et al. Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. Eur J Med Chem. 2020 Dec 1;207:112837.

Density 1.268g/cm3
Boiling Point 414.3ºC at 760mmHg
Molecular Formula C16H10O2
Molecular Weight 234.25
Flash Point 155ºC
Exact Mass 234.06800
PSA 34.14000
LogP 3.14920
Vapour Pressure 4.51E-07mmHg at 25°C
Index of Refraction 1.649
HS Code 2914690090
HS Code 2914690090
Summary 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%