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80307-12-6

80307-12-6 structure

80307-12-6 structure

Name: gmbs
Chemical Name: 4-Maleimidobutyric Acid N-Succinimidyl Ester
CAS Number: 80307-12-6
Molecular Formula: C₁₂H₁₂N₂O₆
Molecular Weight: 280.233
Catalog: Chemical reagent Organic reagent Ester Other ester compounds
Create Date: 2018-11-26 06:18:41
Modify Date: 2026-07-01 17:06:38
GMBS is a heterobifunctional cross-linker. GMBS is often used to prepare antibody-enzyme and hapten-carrier protein conjugates.

Name	4-Maleimidobutyric Acid N-Succinimidyl Ester
Synonyms	CIVENTICHEM CV-2656 2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate 4-Maleimidobutyric acid N-succinimidyl ester, GMBS, N-(γ-Maleimidobutyryloxy)succinimide, N-Succinimidyl 4-maleimidobutyrate 4-MALEIMIDOBUTYRIC ACID N-HYDROXYSUC 1-[4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]-1H-pyrrole-2,5-dione GAMMA-MALEIMIDOBUTYRIC ACID N-HYDROXYSUCCINIMIDE ESTER N-(4-MaleiMidebutyryloxy)succiniMide 2,5-Dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl) 4-MALEIMIDOBUTYRIC ACID N-SUCCINIMIDYL ESTER 4-Maleimidobutyric Acid N-Succinimidyl Ester N-(4-Maleimidobutyryloxy)succinimide N-(4-Maleimidobutyryloxy)succinimide (GMBS) 63MG-F 4-Maleimidobutyric acid N-hydroxysuccinimide ester N-(4-Maleimibutyryloxy)succinimide N-(4-Maleimidobutyryloxy)succinimideN-Succinimidyl-4-maleimidobutyrate N-SUCCINIMIDYL 4-MALEIMIDOBUTYRATE 4-Maleimidobutyric acid N-hydroxysuccinimideester GAMMA-MALEIMIDOBUTYRIC ACID N-HYDROXY-*S UCCINIMIDE 4-Maleimidobutyric Acid N-hydroxysuccinimide Ester extrapure (GMBS) 4-Maleimidobutyric acid N-hydroxysuccinimide ester 1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester 3-MaleiMidobutyric acid N-hydroxysucciniMide ester 4-MaleinimidobutyricacidN-succinimidylester (GMBS):4-Maleimidobutyric acid NHS 4-Maleimidobutyric acid-NHS ester N-Succinimidyl 4-Maleimidobutyrate [Cross-linking ] N-(GAMMA-MALEIMIDOBUTYRYLOXY)SUCCINIMIDE ESTER 4-Maleimidobutyric acid NHS N-(4-MALEIMIDOBUTYRYLOXY)SUCCINIMIDE [MAL-SBA] 2,5-dioxopyrrolidin-1-yl 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoate N-Succinimidyl4-Maleimidobutyrate[Cross-linkineagent]> N-GAMMA-MALEIMIDOBUTYRYLOXYSUCCINIMIDE 1-{4-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione 1-{4-[(2,5-Dioxopyrrolidin-1-yl)oxy]-4-oxobutyl}-1H-pyrrole-2,5-dione 4-MaleiMidobutyric acid N-hydroxysucciniMide ester(GMBS) 4-maleimide butyrate-N-hydroxysuccinimide ester 4-Maleimidobutyric acid n-succinimidyl ester(GMBS) N-Y-MALEIMIDOBUTYRYLOXYSUCCINIMIDE ESTER MFCD00036817 (2,5-dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)butanoate GMBS Crosslinker 4-MaleiMidobutyric Acid N-HydroxysucciMide Ester N-MALEIMIDOBUTYRYLOXYSUCCINIMIDE ESTER 1H-Pyrrole-2,5-dione, 1-[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]-4-oxobutyl]

Description	GMBS is a heterobifunctional cross-linker. GMBS is often used to prepare antibody-enzyme and hapten-carrier protein conjugates.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
References	[1]. Ding YH, et al. Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers. Anal Chem. 2016 Apr 19;88(8):4461-9.

Density	1.5±0.1 g/cm3
Boiling Point	461.3±47.0 °C at 760 mmHg
Melting Point	123-129ºC
Molecular Formula	C₁₂H₁₂N₂O₆
Molecular Weight	280.233
Flash Point	232.8±29.3 °C
Exact Mass	280.069550
PSA	101.06000
LogP	-1.56
Vapour Pressure	0.0±1.1 mmHg at 25°C
Index of Refraction	1.595
Storage condition	2-8°C
Water Solubility	chloroform: 100 mg/mL

Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2925190090

6066-82-6 structure

6066-82-6

57078-98-5 structure

57078-98-5

~%

57-13-6 structure

57-13-6

80307-12-6 structure

80307-12-6

Literature: Organic and Biomolecular Chemistry, , vol. 7, # 17 p. 3400 - 3406

6066-82-6 structure

6066-82-6

57078-98-5 structure

57078-98-5

~%

80307-12-6 structure

80307-12-6

Literature: Bioorganic and Medicinal Chemistry, , vol. 7, # 5 p. 901 - 919

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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