135062-02-1
135062-02-1 structure
- Name: Repaglinide
- Chemical Name: Repaglinide
- CAS Number: 135062-02-1
- Molecular Formula: C27H36N2O4
- Molecular Weight: 452.586
- Catalog: API Hormone and endocrine-regulating drugs Pancreatic hormones and other blood sugar regulating drugs
- Create Date: 2018-07-21 23:07:12
- Modify Date: 2026-06-30 17:23:37
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Repaglinide(AG-EE 623ZW) is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes. IC50 value:Target: Repaglinide is very rapidly absorbed (tmax less than 1 hour) with a t1/2 of less than one hour. Furthermore, repaglinide is inactivated in the liver and more than 90 % excreted via the bile. Repaglinide (1 mg/kg p.o.) was effective (P < 0.001) as an insulin-releasing agent in a rat model (low-dose streptozotocin) of type 2 diabetes.
| Name | Repaglinide |
|---|---|
| Synonyms |
Raglinide API
Benzoic acid, 2-ethoxy-4-(2-((3-methyl-1-(2-(1-piperidinyl)phenyl)butyl)amino)- 2-oxoethyl)-, (S) (S)-2-Ethoxy-4-(2-((3-methyl-1-(2-(piperidin-1-yl)phenyl)butyl)amino)-2-oxoethyl)benzoic acid RAGLINIDE (NON-STERILE DRUG SUBSTANCE) 2-ethoxy-4-[2-keto-2-[[(1S)-3-methyl-1-(2-piperidinophenyl)butyl]amino]ethyl]benzoic acid AG EE-623 ZW NOVONORM 2-ethoxy-4-[2-[[3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid Novonorm, Prandin, (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocbonylmethyl]benzoic acid AG-EE 624ZW Raglinde Reference Standd (S)-(+)-2-Ethoxy-4-[[[N-[1-(2-piperidinophenyl)-3-methylbutyl]amino]carbonyl]methyl]benzoic acid 2-ethoxy-4-(2-{[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino}-2-oxoethyl)benzoic acid ag-ee388zw Raglinde Solution, 100ppm (S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid (S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonylmethyl]benzoic acid (S)-2-ethoxy-4-(2-(3-methyl-1-(2-(piperidin-1-yl)phenyl)butylamino)-2-oxoethyl)benzoic acid Prandin, 2-Ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)butyl]amino]-2-oxoethyl]-benzoic Acid, AG-EE-623, Novonorm (S)-2-ETHOXY-4-(2-(3-METHYL-1-(2-(PIPERIDIN-1-YL)PHENYL)BUTYLAMINO)-2-OXOETHYL)BENZOIC ACID Rebaglinide 2-Ethoxy-4-[2-[[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid Benzenemethanol,α-(aminomethyl)-8-bromo methyl 3-[4-cyano-4-[phenyl(propanoyl)amino]piperidin-1-yl]propanoate Raglinide G0D2760.999mg/mg(ai) (S)-(+)-2-ETHOXY-4-[N-[1-(2-PIPERIDINOPHENYL)-3-METHYL-1-BUTYL]AMINOCBONYLMETHYL]BENZOIC ACID Raglinid 5.2 RAGLINIDE 2-ethoxy-4-({[(1S)-3-Methyl-1-[2-(piperidin-1-yl)phenyl]butyl]cbaMoyl}Methyl)benzoic acid AG-EE-623 PRANDIN Repaglinid Raglinide - Bio-X Raglinide,(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocbonylmethyl]benzoic acid, Novonorm, Prandin 4-Cboxy-3-ethoxybenzeneacetic Acid Prandin,GlucoNorm,NovoNorm 2-Ethoxy-4-[2-({(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid Raglinide //BP Raglinide, 10 mM in DMSO 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxoethyl]benzoic acid Raglinide CRS Raglinide(AG-EE 623ZW) RaglinideQ: What is Raglinide Q: What is the CAS Number of Raglinide Q: What is the storage condition of Raglinide Q: What e the applications of Raglinide Rapaglinide 2-Ethoxy-4-[2-[[(1R)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid C16809400 Raglinide S(+)-2-Ethoxy-4-(2-oxo-2-((alpha-isobutyl-2-piperidinobenzyl)amino)ethyl)benzoesure AG-EE-623 ZW 2-Ethoxy-4-[2-[[(1S)-3-Methyl-1-[2-(1-Piperidinyl)Phenyl]Butyl]Amino]-2-Oxoethyl]Benzoic Acid Raglinide,(S)-(+)-2-Ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocbonylmethyl]benzoic acid, Novon (+)-2-Ethoxy-a-[[(S)-a-isobutyl-o-piperidinobenzyl]carbamoyl]-p-toluic acid MFCD00906179 2-ethoxy-4-[2-[[(1S)-3-methyl-1-(2-piperidin-1-ylphenyl)butyl]amino]-2-oxo-ethyl]benzoic acid 2-ethoxy-4-[2-({(1S)-3-methyl-1-[2-(piperidin-1-yl)phenyl]butyl}amino)-2-oxoethyl]benzoic acid (S)-2-Ethoxy-4-[2-[[3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic acid (S)-2-Ethoxy-4-[2-[[[(1S)-3-Methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl]benzoic Acid Benzoic acid, 2-ethoxy-4-[2-[[(1S)-3-methyl-1-[2-(1-piperidinyl)phenyl]butyl]amino]-2-oxoethyl] Raglinide> 2-ETHOXY-4-[2-[(1S)-3-METHYL-1-[2-(1-PIPERIDINYL)BUTYL]AMINO]-2-OXOETHYL]-BENZOIC ACID Raglinide for system suitability CRS Raglinide in Methanol |
| Description | Repaglinide(AG-EE 623ZW) is a carbamoylmethyl benzoic acid (CMBA) derivative, which recently has become available for the treatment of type II diabetes. IC50 value:Target: Repaglinide is very rapidly absorbed (tmax less than 1 hour) with a t1/2 of less than one hour. Furthermore, repaglinide is inactivated in the liver and more than 90 % excreted via the bile. Repaglinide (1 mg/kg p.o.) was effective (P < 0.001) as an insulin-releasing agent in a rat model (low-dose streptozotocin) of type 2 diabetes. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 672.9±55.0 °C at 760 mmHg |
| Melting Point | 129-130.2 °C |
| Molecular Formula | C27H36N2O4 |
| Molecular Weight | 452.586 |
| Flash Point | 360.8±31.5 °C |
| Exact Mass | 452.267517 |
| PSA | 78.87000 |
| LogP | 4.69 |
| Vapour Pressure | 0.0±2.2 mmHg at 25°C |
| Index of Refraction | 1.568 |
| Storage condition | 2-8°C |
| Water Solubility | DMSO: 34 mg/mL |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| Hazard Codes | Xn |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | 000000033825 |
| HS Code | 2933399090 |
| Precursor 5 | |
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| DownStream 0 | |
| HS Code | 2933399090 |
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| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |