Fmoc-PEG3-alcohol

Modify Date: 2024-01-03 10:44:15

Fmoc-PEG3-alcohol Structure
Fmoc-PEG3-alcohol structure
Common Name Fmoc-PEG3-alcohol
CAS Number 560088-66-6 Molecular Weight 371.42700
Density 1.208g/cm3 Boiling Point 581.5ºC at 760 mmHg
Molecular Formula C21H25NO5 Melting Point N/A
MSDS N/A Flash Point 305.5ºC

 Use of Fmoc-PEG3-alcohol


Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 9H-fluoren-9-ylmethyl N-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]carbamate
Synonym More Synonyms

 Fmoc-PEG3-alcohol Biological Activity

Description Fmoc-PEG3-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

 Chemical & Physical Properties

Density 1.208g/cm3
Boiling Point 581.5ºC at 760 mmHg
Molecular Formula C21H25NO5
Molecular Weight 371.42700
Flash Point 305.5ºC
Exact Mass 371.17300
PSA 77.02000
LogP 2.94150
Index of Refraction 1.572

 Synonyms

og002
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