125678-68-4

125678-68-4 structure

Name: Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
Chemical Name: (2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
CAS Number: 125678-68-4
Molecular Formula: C₄₂H₈₂N₁₂O₈
Molecular Weight: 883.17600
Catalog: Signaling Pathways Epigenetics PKC
Create Date: 2018-12-30 19:01:25
Modify Date: 2024-01-02 15:17:40
N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].

Name	(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-6-amino-2-(tetradecanoylamino)hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]amino]-4-methylpentanoyl]amino]-5-(diaminomethylideneamino)pentanoic acid
Synonyms	N-Myristoyl-lysyl-arginyl-threonyl-leucyl-arginine MYRISTOYL-KRTLR-OH Mlatla MYRISTOYL-KRTLR-OH INHIBITOR OF PKC N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH N-Myristyl-lys-arg-thr-leu-arg N2-(N-(N-(N2-(N2-(1-Oxotetradecyl)-L-lysyl)-L-arginyl)-L-threonyl)-L-leucyl)-L-arginine

Description	N-Myristoyl-Lys-Arg-Thr-Leu-Arg is a protein kinase C (PKC) inhibitor with an IC50 value of 75 μM. N-Myristoyl-Lys-Arg-Thr-Leu-Arg inhibits IL-2 receptor induction and IL-2 production in the human leukemic cell line Jurkat[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Inflammation/Immunology Signaling Pathways >> TGF-beta/Smad >> PKC
In Vitro	N-Myristoyl-Lys-Arg-Thr-Leu-Arg (0-50 μM) inhibits the production and release of IL-2 from cultured Jurkat cells stimulated with TPA plus either PHA or OKT3 mAb[1].