- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: CP 80633
- Price:
- Purity: 99.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: Atizoram
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 5-[4-methoxy-3-[(2S)-norbornan-2-yl]oxy-phenyl]-1,3-diazinan-2-one
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
135637-46-6
135637-46-6 structure
- Name: CP 80633
- Chemical Name: 5-[3-[[(3S)-3-bicyclo[2.2.1]heptanyl]oxy]-4-methoxyphenyl]-1,3-diazinan-2-one
- CAS Number: 135637-46-6
- Molecular Formula: C18H24N2O3
- Molecular Weight: 316.395
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
- Create Date: 2016-12-13 07:22:46
- Modify Date: 2024-01-09 17:00:57
-
Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice[1].
| Name | 5-[3-[[(3S)-3-bicyclo[2.2.1]heptanyl]oxy]-4-methoxyphenyl]-1,3-diazinan-2-one |
|---|---|
| Synonyms |
3-Methyl-GABA
5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydropyrimidin-2(1H)-one Atizoram UNII-O84FJB49WI 2(1H)-Pyrimidinone, 5-[3-[(1S,2S,4R)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro- 5-(3-((1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy)-4-(methyloxy)phenyl)tetrahydro-2(1H)-pyrimidinone Tetrahydro-5-(4-methoxy-3-((1S,2S,4R)-2-norbomyloxy)phenyl)-2(1H)-pyrimidinone 5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydro-2(1H)-pyrimidinone |
| Description | Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice[1]. |
|---|---|
| Related Catalog | |
| Target |
PDE4 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 543.0±50.0 °C at 760 mmHg |
| Molecular Formula | C18H24N2O3 |
| Molecular Weight | 316.395 |
| Flash Point | 282.2±30.1 °C |
| Exact Mass | 316.178680 |
| PSA | 59.59000 |
| LogP | 2.46 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.560 |
|
~74%
135637-46-6 |
| Literature: US6399776 B2, ; Page column 18,19 ; |
| Precursor 1 | |
|---|---|
| DownStream 0 | |