CP 80633

Modify Date: 2024-01-09 17:00:57

CP 80633 structure	Common Name	CP 80633
	CAS Number	135637-46-6	Molecular Weight	316.395
	Density	1.2±0.1 g/cm3	Boiling Point	543.0±50.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₂₄N₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	282.2±30.1 °C

Use of CP 80633

Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice[1].

Name	5-[3-[[(3S)-3-bicyclo[2.2.1]heptanyl]oxy]-4-methoxyphenyl]-1,3-diazinan-2-one
Synonym	More Synonyms

Description	Atizoram (CP-80,633), a cyclic nucleotide phosphodiesterase (PDE4) inhibitor, elevates plasma cyclic AMP levels and decreases tumor necrosis factor-α (TNFα) production in mice[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
Target	PDE4
References	[1]. J B Cheng, et al. The phosphodiesterase type 4 (PDE4) inhibitor CP-80,633 elevates plasma cyclic AMP levels and decreases tumor necrosis factor-alpha (TNFalpha) production in mice: effect of adrenalectomy. J Pharmacol Exp Ther. 1997 Feb;280(2):621-6.

Density	1.2±0.1 g/cm3
Boiling Point	543.0±50.0 °C at 760 mmHg
Molecular Formula	C₁₈H₂₄N₂O₃
Molecular Weight	316.395
Flash Point	282.2±30.1 °C
Exact Mass	316.178680
PSA	59.59000
LogP	2.46
Vapour Pressure	0.0±1.5 mmHg at 25°C
Index of Refraction	1.560

3-(3-[(2S)-exo-...

CAS#:135637-45-5

~74%

CP 80633

CAS#:135637-46-6

Literature: US6399776 B2, ; Page column 18,19 ;

Precursor 1
CAS#:135637-45-5 3-(3-[(2S)-exo-...
DownStream 0

3-Methyl-GABA

5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydropyrimidin-2(1H)-one

Atizoram

UNII-O84FJB49WI

2(1H)-Pyrimidinone, 5-[3-[(1S,2S,4R)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl]tetrahydro-

5-(3-((1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy)-4-(methyloxy)phenyl)tetrahydro-2(1H)-pyrimidinone

Tetrahydro-5-(4-methoxy-3-((1S,2S,4R)-2-norbomyloxy)phenyl)-2(1H)-pyrimidinone

5-{3-[(1S,2S,4R)-Bicyclo[2.2.1]hept-2-yloxy]-4-methoxyphenyl}tetrahydro-2(1H)-pyrimidinone

DC Chemicals Limited
China
Product Name: Atizoram
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5-[4-methoxy-3-[(2S)-norbornan-2-yl]oxy-phenyl]-1,3-diazinan-2-one
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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CP 80633

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