Name | PrP [106-126] |
---|---|
Synonyms |
Prion Protein Fragment 106-126 Human
N-MPPP Hydrochloride |
Description | Prion Protein 106-126 (human) is a peptide fragment of prion, it can induct neuronal apoptosis, antiproteinase K digestion, fiber formation, and mediate the conversion of normal cellular prion protein (PrPc) into pathogenic isoform (PrPSc). Prion Protein 106-126 (human) is generally used as the model to investigate neural degeneration of prion disease[1][2]. |
---|---|
Related Catalog | |
References |
[1]. Forloni G, et, al. Neurotoxicity of a prion protein fragment. Nature. 1993 Apr 8; 362(6420): 543-6. |
Molecular Formula | C80H138N26O24S2 |
---|---|
Molecular Weight | 1912.24000 |
Exact Mass | 1910.98000 |
PSA | 839.96000 |
LogP | 0.33420 |
Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
---|---|
Safety Phrases | S22-S24/25 |
RIDADR | NONH for all modes of transport |