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950683-55-3

950683-55-3 structure
950683-55-3 structure
  • Name: Boc-N-Amido-PEG2-C2-azide
  • Chemical Name: Carbamic acid, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
  • CAS Number: 950683-55-3
  • Molecular Formula: C11H22N4O4
  • Molecular Weight: 274.31700
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-08-22 23:26:57
  • Modify Date: 2024-01-10 18:15:34
  • Boc-N-Amido-PEG2-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name Carbamic acid, N-[2-[2-(2-azidoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
Synonyms BOC-NH-PEG(2)-N3 1-(T-BUTYLOXYCARBONYL-AMINO)-3,6-DIOXA-8-OCTANEAZIDE
tert-Butyl 2-(2-azidoethoxy)ethoxyethylcarbamate
Description Boc-N-Amido-PEG2-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H22N4O4
Molecular Weight 274.31700
Exact Mass 274.16400
PSA 106.54000
LogP 1.69826
Precursor  0

DownStream  3