153086-78-3

153086-78-3 structure

Name: N-BOC-2,2′-(ethylenedioxy)bis(ethylamine)
Chemical Name: tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
CAS Number: 153086-78-3
Molecular Formula: C₁₁H₂₄N₂O₄
Molecular Weight: 248.319
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-11-24 17:52:29
Modify Date: 2026-07-03 18:15:23
PROTAC Linker 13 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 13 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Name	tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]carbamate
Synonyms	CBZ-L-Asginine-OH Hydrochloride Boc-1-amino-3,6-dioxa-8-octanediamine(Boc-NH-PEG3) 1-(T-BUTYLOXYCBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE, LIQ NHBoc-PEG2-amine Boc-NH-PEG2-CH2CH2NH2 t-BocNH-PEG2-CH2CH2NH2 5,8-dioxa-2-azadihtaoic acid, 10-amino-,1,1-diMethylethyl ester Boc-1-amino-3,6-dioxa-8-octanediamine (Titration) tert-butyl N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]cbamate N-Boc- 2,2′-(ethylenedioxy)diethylamine 1-(T-BUTYLOXYCBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE Boc-N-amido-PEG2-Amine,t-boc-N-amido-PEG2-amine Boc-NH-PEG3 Boc-1-amino-3,6-dioxa-8-octanediamine tert-Butyl (2-(2-(2-aminoethoxy) BOC-1-AMINO-3,6-DIOXA-8-OCTANEDIAMINE N-Boc-3,6-dioxa-1,8-octanediamine N-Boc-2-[2-(2-amino-ethoxy)-etho NH2-PEG2-NHBOC N-Boc-2,2’-(ethylenedioxy)diethylamine 1-(TERT-BUTYLOXYCBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE, LIQ t-Boc-N-amido-PEG2-Amine PROTAC Linker 13 N-Boc- 2,2′-(ethylenedioxy)diethylamine, >= N-BOC-2,2'-(ETHYLENEDIOXY)DIETHYLAMINE t-Boc-Amido-PEG3-Amine Boc-N-amido-PEG2-Amine t-boc-N-amido-PEG2-amin 2-Methyl-2-propanyl {2-[2-(2-aminoethoxy)ethoxy]ethyl}carbamate BOC-NH-PEG2-NH2 1-(TERT-BUTYLOXYCBONYL-AMINO)-3,6-DIOXA-8-OCTANEAMINE TERT-BUTYL 2-[2-(2-AMINOETHOXY)ETHOXY]ETHYLCBAMATE N-(tert-Butoxycbonyl)-2,2'-(ethylenedioxy)diethylamine N-(tert-Butoxycbonyl)-3,6-dioxa-1,8-octanediamine BOC-N-AMIDO-PEG2-NH2 AmbotzBNN1016 {2-[2-(2-Amino-ethoxy)-ethoxy]-ethyl}-cbaMic acid tert-butyl ester Boc-N-amido-PEG2-Amine N-tert-Butyloxycbonyl-1,8-diamino-3,6-dioxaoctane NHBoc-PEG3-NH2 Carbamic acid, N-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester N-Boc- 2,2'-(ethylenedioxy)diethylaMine >= (NT) BOC-DOOA CbaMic acid,N-[2-[2-(2-aMinoethoxy)ethoxy]ethyl]-, 1,1-diMethylethyl ester N-Boc-3,6-dioxaoctane-1,8-diamine N-BOC-3,6-DIOXA-1,8-OCTANEDIAMINE N-Boc-2-[2-(2-amino-ethoxy)-ethoxy]-ethylamine

Description	PROTAC Linker 13 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 13 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Density	1.0±0.1 g/cm3
Boiling Point	365.2±27.0 °C at 760 mmHg
Molecular Formula	C₁₁H₂₄N₂O₄
Molecular Weight	248.319
Flash Point	174.6±23.7 °C
Exact Mass	248.173615
PSA	82.81000
LogP	0.19
Vapour Pressure	0.0±0.8 mmHg at 25°C
Index of Refraction	1.460

Personal Protective Equipment	Eyeshields;Gloves
RIDADR	NONH for all modes of transport
WGK Germany	3

Precursor 10
929-59-9 24424-99-5 950683-55-3 796865-54-8
58632-95-4 556065-62-4 6627-89-0 556065-61-3
1245727-44-9 59559-06-7
DownStream 5
166388-57-4 660843-23-2 918827-51-7 923567-96-8
627539-91-7

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