- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Propynol Ethoxylate
- Price: ￥138.0/5g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Propargyl-PEG2-alcohol
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Propynol ethoxylate
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Zhejiang Hangyu API Co., Ltd
- China
- Product Name: Propynol ethoxylate
- Price: ￥Inquiry/1kg
- Purity: 99.5%
- Stocking Period: Inquiry
- Contact: Vinnie
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Propynol Ethoxylate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Stocking Period: Inquiry
- Contact: Anson
3973-18-0
3973-18-0 structure
- Name: Propynol Ethoxylate
- Chemical Name: Propynol Ethoxylate
- CAS Number: 3973-18-0
- Molecular Formula: C5H8O2
- Molecular Weight: 100.116
- Catalog: Signaling Pathways PROTAC PROTAC Linker
- Create Date: 2018-07-12 08:28:53
- Modify Date: 2024-01-04 12:03:57
-
Propynol Ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
| Name | Propynol Ethoxylate |
|---|---|
| Synonyms |
MFCD06411441
EINECS 223-601-1 2-(2-Propyn-1-yloxy)ethanol Propynol ethoxylate Ethanol, 2-(2-propyn-1-yloxy)- 2-(Prop-2-yn-1-yloxy)ethanol PME |
| Description | Propynol Ethoxylate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 168.7±15.0 °C at 760 mmHg |
| Molecular Formula | C5H8O2 |
| Molecular Weight | 100.116 |
| Flash Point | 68.9±14.6 °C |
| Exact Mass | 100.052429 |
| PSA | 29.46000 |
| LogP | -0.25 |
| Vapour Pressure | 0.5±0.7 mmHg at 25°C |
| Index of Refraction | 1.446 |
| Storage condition | -20°C |
|
~60%
3973-18-0 |
| Literature: Kislukhin, Alexander A.; Higginson, Cody J.; Hong, Vu P.; Finn Journal of the American Chemical Society, 2012 , vol. 134, # 14 p. 6491 - 6497 |
|
~%
3973-18-0 |
| Literature: RIB-X PHARMACEUTICALS, INC. Patent: WO2004/29066 A2, 2004 ; Location in patent: Page/Page column 281 ; |
|
~67%
3973-18-0 |
| Literature: Bovicelli; Mincione; Patamia Synthetic Communications, 1991 , vol. 21, # 7 p. 907 - 913 |
|
~%
3973-18-0 |
| Literature: Hoffmann-La Roche Inc. Patent: US6130239 A1, 2000 ; US 6130239 A |
|
~%
3973-18-0 |
| Literature: Erver, Florian; Kuttner, Julian R.; Hilt, Gerhard Journal of Organic Chemistry, 2012 , vol. 77, # 19 p. 8375 - 8385 |
|
~%
3973-18-0 |
| Literature: Faure,R.; Descotes,G. Bulletin de la Societe Chimique de France, 1966 , p. 1569 - 1575 Full Text Show Details Bottini,A.T. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 2988 - 2994 |
|
~%
3973-18-0 |
| Literature: Atavin,A.S. et al. Journal of Organic Chemistry USSR (English Translation), 1967 , vol. 3, p. 10 - 12 Zhurnal Organicheskoi Khimii, 1967 , vol. 3, # 1 p. 12 - 15 |
|
~%
3973-18-0 |
| Literature: Pola,J. et al. Collection of Czechoslovak Chemical Communications, 1978 , vol. 43, p. 760 - 768 |
| Precursor 10 | |
|---|---|
| DownStream 4 | |
![2-(3-bicyclo[2.2.1]hepta-2,5-dienylmethoxy)ethanol structure](https://www.chemsrc.com/caspic/143/69392-36-5.png)
