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2086-83-1

2086-83-1 structure
2086-83-1 structure
  • Name: Berberine
  • Chemical Name: berberine
  • CAS Number: 2086-83-1
  • Molecular Formula: C20H18NO4+
  • Molecular Weight: 336.361
  • Catalog: Biochemical Chinese herbal medicine ingredients
  • Create Date: 2018-09-25 17:19:12
  • Modify Date: 2026-06-30 18:22:45
  • Berberine is a natural alkaline, reduces apoptosis, with potent anti-oxidative and anti-inflammatory effect[1].
Name berberine
Synonyms 9,10-Dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium
InsipBerberine
Rhizoma Coptidis extract
Berberine D6
BERBERINE
BERBERINE HYDROCHLORIDE N-HYDRATE
5,6-dihydro-9,10-dimethoxy-1,3-benzodioxolo[5,6-a]benzo[g]quinolizinium
7,8,13,13a-tetrahydro-9,10-dimethoxy-2,3-(methylenedioxy)-berbiniu
7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium
Dried Coptidis Rhizoma Extract
2-1 Berberine
EINECS 211-195-9
UMBELLATINE
Berberine //BP
NATURAL YELLOW 18 CHLORIDE
5,6-dihydro-9,10-dimethoxy-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo-[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium
LABOTEST-BB LT00440956
Coptis chinensis extract
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium
Berberine (base and/or unspecified salts)
Chinese Goldthread Extract
berberin
9,10-dimethoxy-2,3-(methylenedioxy)-7,8,13,13a-tetrahydroberbinium
5,6-Dihydro-9,10-dimethoxybenzo[g]1,3-benzodioxolo[5,6-a]quinolizinium
Berberine iodide salt
3-Oxo-5β-cholanoic acid sodium
Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy
9,10-dimethoxy-5,6-dihydro[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolin-7-ium
Berberin
9,10-Dimethoxy-5,6-dihydro-[1,3]dioxolo-[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium DISCONTINUED. offer B318150
Berberine (unspecified form)
7,8,13,13a-Tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)berbinium
BERBERIN HCL
Coptis extract
Coptisrootextract
5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6]quinolizinium
beriberi
5,6-DIHYDRO-9,10-DIMETHOXY-BENZO[G]-1,3-BENZODIOXOLO[5,6-A]QUINOLIZINIUM, CHLORIDE
Berbericine
Berberine, 10 mM in DMSO
7,8,13,13-Tetradehydro-9.10-dimethoxy-2,3-(methylenedioxy)berbinium
BERBERINE HCL
TIMTEC-BB SBB006488
13C,-Berberine iodide salt
MFCD00011939
Description Berberine is a natural alkaline, reduces apoptosis, with potent anti-oxidative and anti-inflammatory effect[1].
Related Catalog
References

[1]. Ma X, et al. Berberine exhibits antioxidative effects and reduces apoptosis of the vaginal epithelium in bacterial vaginosis. Exp Ther Med. 2019 Sep;18(3):2122-2130.
Melting Point 204-206ºC (dec.)
Molecular Formula C20H18NO4+
Molecular Weight 336.361
Exact Mass 336.123047
PSA 40.80000
LogP -0.99

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DR9870000
CHEMICAL NAME :
Berbinium, 7,8,13,13a-tetrahydro-9,10-dimethoxy-2,3-(methylenedi oxy)-
CAS REGISTRY NUMBER :
2086-83-1
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C20-H18-N-O4
MOLECULAR WEIGHT :
336.39
WISWESSER LINE NOTATION :
T F5 D6 C666 GO IO ON HH&&T&&J RO1 SO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
329 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
18 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
10 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981
Hazard Codes Xi
Safety Phrases S24/25
RIDADR UN 1544
WGK Germany 2
RTECS DR9866400
Packaging Group III
Hazard Class 6.1(b)
HS Code 2934999090
HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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