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86694-45-3

86694-45-3 structure
86694-45-3 structure
  • Name: preQ1 Dihydrochloride
  • Chemical Name: 2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride
  • CAS Number: 86694-45-3
  • Molecular Formula: C7H10ClN5O
  • Molecular Weight: 215.64000
  • Catalog: Research Areas Metabolic Disease
  • Create Date: 2018-01-23 05:07:25
  • Modify Date: 2024-01-31 22:39:20
  • preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].

Name 2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride
Synonyms 7-aminomethyl-7-deazaguanine dihydrochloride
preQ1 Dihydrochloride
Description preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].
Related Catalog
References

[1]. Connelly CM, et al. Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun. 2019 Apr 2;10(1):1501.  

Molecular Formula C7H10ClN5O
Molecular Weight 215.64000
Exact Mass 215.05700
PSA 113.58000
LogP 1.37560
Storage condition 2-8°C
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xn
Risk Phrases 22-36/37/38
RIDADR NONH for all modes of transport