preQ1 Dihydrochloride

Modify Date: 2025-09-03 23:31:19

preQ1 Dihydrochloride Structure
preQ1 Dihydrochloride structure
Common Name preQ1 Dihydrochloride
CAS Number 86694-45-3 Molecular Weight 215.64000
Density N/A Boiling Point N/A
Molecular Formula C7H10ClN5O Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of preQ1 Dihydrochloride


preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].

 Names

Name 2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one dihydrochloride
Synonym More Synonyms

 preQ1 Dihydrochloride Biological Activity

Description preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].
Related Catalog
References

[1]. Connelly CM, et al. Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun. 2019 Apr 2;10(1):1501.  

 Chemical & Physical Properties

Molecular Formula C7H10ClN5O
Molecular Weight 215.64000
Exact Mass 215.05700
PSA 113.58000
LogP 1.37560
Storage condition 2-8°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Hazard Codes Xn
Risk Phrases 22-36/37/38
RIDADR NONH for all modes of transport

 Synonyms

7-aminomethyl-7-deazaguanine dihydrochloride
preQ1 Dihydrochloride
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