58822-25-6
58822-25-6 structure
- Name: Leu-Enkephalin
- Chemical Name: [leu5]-enkephalin
- CAS Number: 58822-25-6
- Molecular Formula: C28H37N5O7
- Molecular Weight: 555.62300
- Catalog: Biochemical Common amino acids and protein drugs
- Create Date: 2018-05-29 08:00:00
- Modify Date: 2026-07-03 10:42:08
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[Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
| Name | [leu5]-enkephalin |
|---|---|
| Synonyms |
DYNORPHIN A
enkhalin,leucine Leu5]-Enkhalin, amide acetate EINECS 261-457-1 leuthine enkhalin Leu-Enkhalin,α-Neoendorphin , Dynorphin A ALPHA-NEOENDORPHIN [5-LEUCINE]ENKHALIN H-TYR-GLY-GLY-PHE-LEU-OH amide acetate(60-0 free base) LEUCINE-ENKHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE) [LEU5]-ENKHALIN //BP Tyr-Gly-Gly-Phe-Leu-OH Leu-Enkhalin acetate ENKEPHALIN L [Leu5]-Enkhalin acetate(58-6 free base) ENKHALIN L a-Neoendorphin , Dynorphin A H2N-Tyr-Gly-Gly-Phe-Leu-COOH [Leu5]Enkhalin, amide acetate,[Leu-5]-Enkhalin, amide acetate,[Leu5] Enkhalin, amide acetate Leucyl-enkhalin amide acetate [Leu5]-Enkhalin,Tyr-Gly-Gly-Phe-Leu,YGGFL,ICI-114740,Leu-enkhalin,Leucine enkhalin,Leucyl-enkhalin, BR [Leu5]-Enkhalin, delta and mu-rector agonist L-leucine enkephalin LEU-ENKHALIN Leu-Enkhalin,α-Neoendorphin TYR-GLY-GLY-PHE-LEU H2O [LEU5]-ENKHALIN [5-Leucine]Enkhalin, Enkhalin L [Leu5] Enkhalin acetate,[Leu5]Enkhalin acetate,[Leu-5]-Enkhalin acetate(58-6 free base) LEUCINE-ENKEPHALIN (5-LEUCINE)ENKHALIN MFCD00076406 Leucine enkhalin|||Leu-enkhalin|||Leucyl-enkhalin TYR-GLY-GLY-PHE-LEU L-Tyr-Gly-Gly-L-Phe-L-Leu-OH LEU-ENKEPHALIN L-Leucine, L-tyrosylglycylglycyl-L-phenylalanyl N-[N-[N-(N-L-tyrosylglycyl)glycyl]-L-phenylalanyl]-L-leucine H-TyrGlyGlyPheLeu-OH L-TYR-GLY-GLY-PHE-LEU SGS 518 oxalate leucine enkhalin acetate hydrate (5-LEUCIN)ENKHALIN Leu-Enkelphalin enkephalin,leucine Leu-Enkelphalin Tyr-Gly-Gly-Phe-Leu YGGFL ENKHALIN, LEU5-, HUMAN LEUCINE-ENKHALIN Leu5]-Enkhalin，Tyr-Gly-Gly-Phe-Leu，YGGFL，ICI-114740，Leu-enkhalin，Leucine enkhalin，Leucyl-enkhalin LEUCINE-ENKHALIN (HUMAN, PORCINE, BOVINE, RAT, MOUSE) H2O |
| Description | [Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. |
|---|---|
| Related Catalog | |
| Target |
Opioid receptors[1] |
| In Vitro | Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas[1].Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain[2]. |
| References |
[1]. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. |
| Density | 1.274 g/cm3 |
|---|---|
| Boiling Point | 998.8ºC at 760 mmHg |
| Molecular Formula | C28H37N5O7 |
| Molecular Weight | 555.62300 |
| Flash Point | 557.8ºC |
| Exact Mass | 555.26900 |
| PSA | 199.95000 |
| LogP | 2.10130 |
| Index of Refraction | 1.586 |
| Storage condition | −20°C |
| Water Solubility | Soluble in water (1 mg/ml ). |
| Safety Phrases | S22-S24/25 |
|---|---|
| WGK Germany | 3 |
| Precursor 5 | |
|---|---|
| DownStream 7 | |
