Leu-Enkephalin

Modify Date: 2024-01-03 16:40:15

Leu-Enkephalin structure	Common Name	Leu-Enkephalin
	CAS Number	58822-25-6	Molecular Weight	555.62300
	Density	1.274 g/cm3	Boiling Point	998.8ºC at 760 mmHg
	Molecular Formula	C₂₈H₃₇N₅O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	557.8ºC

Use of Leu-Enkephalin

[Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.

Name	[leu5]-enkephalin
Synonym	More Synonyms

Description	[Leu5]-Enkephalin is a pentapeptides with morphine like properties. [Leu5]-Enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Peptides Research Areas >> Neurological Disease
Target	Opioid receptors[1]
In Vitro	Enkephalins (met- , leu-enkephalin, and enkephalin 8) and dynorphins are two classes of opioid peptides found in the spinal dorsal horn. Mu, delta, and kappa are three major subtypes of opioid receptors. Enkephalins are putative endogenous ligands for delta opioid receptors, and dynorphins are endogenous ligands for the kappa opioid receptors. Three receptor types resembling the vertebrate δ- and κ-type opioid receptors have been characterized pharmacologically in nervous tissues (e.g. Ki=18.9 nM for Leu-enkephalin) and localized by autoradiography at CHH terminals in the SG of C. maenas[1].Leucine-enkephalin is a pentapeptides with morphine like properties, naturally present in mammalian brain[2].
References	[1]. Leu-enkephalin is a five amino acid endogenous peptide that acts as an agonist at opioid receptors. [2]. Meunier JC, et al. Binding of Leu5-enkephalin and Met5-enkephalin to a particulate fraction from rat cerebrum. FEBS Lett. 1977 May 15;77(2):209-13.

Density	1.274 g/cm3
Boiling Point	998.8ºC at 760 mmHg
Molecular Formula	C₂₈H₃₇N₅O₇
Molecular Weight	555.62300
Flash Point	557.8ºC
Exact Mass	555.26900
PSA	199.95000
LogP	2.10130
Index of Refraction	1.586
Storage condition	−20°C
Water Solubility	Soluble in water (1 mg/ml ).

Safety Phrases	S22-S24/25
WGK Germany	3

Precursor 5
CAS#:75244-08-5 4-nitrobenzyl g... CAS#:69729-07-3 Gly-Gly-Phe-Leu-OBn CAS#:63649-15-0 L-phenylalanyl-... CAS#:73994-89-5 Gly-Phe-Leu-OBn
CAS#:77427-00-0 Boc-Tyr-Gly-Gly...
DownStream 7
CAS#:61-90-5 L-leucine CAS#:60254-82-2 H-Tyr-Gly-Gly-Phe-OH CAS#:6234-26-0 H-Gly-Gly-Phe-OH CAS#:60-18-4 L-Tyrosine
CAS#:328-39-2 2-Amino-4-methy... CAS#:100-02-7 4-Nitrophenol CAS#:80632-52-6 Leu-Enkephalin ...

LEU-ENKEPHALIN

H-TyrGlyGlyPheLeu-OH

EINECS 261-457-1

L-TYR-GLY-GLY-PHE-LEU

SGS 518 oxalate

LEUCINE-ENKEPHALIN

Leu-Enkelphalin

L-leucine enkephalin

enkephalin,leucine

MFCD00076406

ENKEPHALIN L

TYR-GLY-GLY-PHE-LEU

YGGFL

H2N-Tyr-Gly-Gly-Phe-Leu-COOH

GL Biochem (Shanghai) Ltd.
China
Product Name: YGGFL
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: [Leu5]Enkephalin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Leu-Enkephalin
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

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Price: $66/10mM*1mLinDMSO

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