23893-13-2

23893-13-2 structure

Name: Anhydroerythromycin A
Chemical Name: Anhydro Erythromycin A
CAS Number: 23893-13-2
Molecular Formula: C₃₇H₆₅NO₁₂
Molecular Weight: 715.911
Catalog: analytical chemistry Analytical reagent Ion chromatography reagent
Create Date: 2017-04-29 17:50:25
Modify Date: 2024-01-03 21:11:38
Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.

Name	Anhydro Erythromycin A
Synonyms	Erythromycin Anhydride,Impurity D (1S,2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-ethyl-3-hydroxy-9-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahyd ;ro-2H-pyran-2-yl]oxy}-2,4,8,10,12,14-hexamethyl-6,15,16-trioxatricyclo[10.2.1.1]hexadecan-7-one (non-preferred name) Erythromycin,9-deoxo-6,12-dideoxy-6,9:9,12-diepoxy ANHYDROERYTHROMYCIN A EM 202 9-Deoxo-6,12-dideoxy-6,9:9,12-diepoxy-erythromycin Erythromycin anhydride Anhydroerythromycin (1S,2R,3R,4S,5R,8R,9S,10S,11R,12R,14R)-11-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-5-ethyl-3-hydroxy-9-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahyd ;ro-2H-pyran-2-yl]oxy}-2,4,8,10,12,14-hexamethyl-6,15,16-trioxatricyclo[10.2.1.1]hexadecan-7-one 6,9,12-Anhydroerythromycin A 6,9:9,12-Diepoxy-9-deoxo-6,12-dideoxyerythromycin

Description	Anhydroerythromycin A is a degradation product of the macrolide antibiotic erythromycin. Anhydroerythromycin A is formed via degradation of erythromycin in acidic aqueous solutions in vitro as well as in vivo. Anhydroerythromycin A is active against S. aureus and B. cereus in vitro (MICs = 12.5 and 6.25 μg/ml, respectively). Anhydroerythromycin A also inhibits steroid 6β-hydroxylase activity associated with the cytochrome P450 (CYP) isoform CYP3A in human liver microsomes.