21233-18-1

21233-18-1 structure

Name: Amaroswerin
Chemical Name: amaroswerin
CAS Number: 21233-18-1
Molecular Formula: C₂₉H₃₀O₁₄
Molecular Weight: 602.54000
Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
Create Date: 2018-04-08 20:41:38
Modify Date: 2025-09-16 21:35:26
Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells[1].

Name	amaroswerin
Synonyms	3,5,3'-Trihydroxy-biphenyl-2-carboxylic acid (2S,3R,4S,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-2-((3S,4R,4aR)-4a-hydroxy-8-oxo-4-vinyl-4,4a,5,6-tetrahydro-3H,8H-pyrano[3,4-c]pyran-3-yloxy)-tetrahydro-pyran-3-yl ester

Description	Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> NO Synthase Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
References	[1]. Yuan Xiang, et al. Anti-inflammatory activity of compounds isolated from Swertia mussotii. Nat Prod Res. 2019 Feb;33(4):598-601. [2]. Satyendra Suryawanshi, et al. Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. Phytother Res. 2009 Jul;23(7):1036-8.