Amaroswerin

Modify Date: 2024-01-11 19:46:43

Amaroswerin Structure
Amaroswerin structure
Common Name Amaroswerin
CAS Number 21233-18-1 Molecular Weight 602.54000
Density N/A Boiling Point N/A
Molecular Formula C29H30O14 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amaroswerin


Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells[1].

 Names

Name amaroswerin
Synonym More Synonyms

 Amaroswerin Biological Activity

Description Amaroswerin is a bioactive secoiridoid glucoside from Swertia mussotii. Amaroswerin has anti-inflammatory, antidiabetic, antiviral, anticholinergic and immunomodulatory activities. Amaroswerin inhibits NO release with an IC50 value of 5.42 μg/mL in RAW264.7 cells[1].
Related Catalog
References

[1]. Yuan Xiang, et al. Anti-inflammatory activity of compounds isolated from Swertia mussotii. Nat Prod Res. 2019 Feb;33(4):598-601.

[2]. Satyendra Suryawanshi, et al. Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits. Phytother Res. 2009 Jul;23(7):1036-8.

 Chemical & Physical Properties

Molecular Formula C29H30O14
Molecular Weight 602.54000
Exact Mass 602.16400
PSA 221.90000
LogP 0.17180

 Synonyms

3,5,3'-Trihydroxy-biphenyl-2-carboxylic acid (2S,3R,4S,5S,6R)-4,5-dihydroxy-6-hydroxymethyl-2-((3S,4R,4aR)-4a-hydroxy-8-oxo-4-vinyl-4,4a,5,6-tetrahydro-3H,8H-pyrano[3,4-c]pyran-3-yloxy)-tetrahydro-pyran-3-yl ester