| Name | sinensetin |
|---|---|
| Synonyms |
6-hydroxyluteolin 5,6,7,3',4'-pentamethyl ether
MFCD00017421 3',4',5,6,7-PENTAMETHOXYFLAVONE Sinensetin 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy- 5,6,7,3',4'-pentamethoxyflavanone 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one Pedalitin permethyl ether 5,6,7,3',4'-Pentamethoxyflavone 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one Sinenstein |
| Description | Sinensetin is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.In vitro: Sinensetin promots adipogenesis in 3T3-L1 preadipocytes growing in incomplete differentiation medium, sinensetin enhances adipogenesis and lipolysis by increasing cAMP levels. [1] Sinensetin shows anti-inflammatory activity by regulating the protein level of inhibitor κB-α (IκB-α). [2]In vivo: Sinensetin has the most potent antiangiogenesis activity and the lowest toxicity, inhibits angiogenesis by inducing cell cycle arrest in the G0/G1 phase in HUVEC culture and downregulating the mRNA expressions of angiogenesis genes flt1, kdrl, and hras in zebrafish. [3] |
|---|---|
| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 547.8±50.0 °C at 760 mmHg |
| Melting Point | 174-176ºC |
| Molecular Formula | C20H20O7 |
| Molecular Weight | 372.369 |
| Flash Point | 240.6±30.2 °C |
| Exact Mass | 372.120911 |
| PSA | 76.36000 |
| LogP | 3.08 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.566 |
| Storage condition | 2-8°C |
| Symbol |
GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 |
| Hazard Codes | T |
| Risk Phrases | 25 |
| Safety Phrases | 22-24/25 |
| RIDADR | UN 2811 6.1 / PGIII |
| HS Code | 2914509090 |
| HS Code | 2914509090 |
|---|---|
| Summary | HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0% |