52438-21-8

52438-21-8 structure

Name: Cinnamopyrrolidide
Chemical Name: Pyrrolidine, 1-cinnamoyl-
CAS Number: 52438-21-8
Molecular Formula: C₁₃H₁₅NO
Molecular Weight: 201.264
Catalog: Natural product Alkaloid
Create Date: 2018-03-12 01:44:05
Modify Date: 2024-01-04 10:56:44
1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].

Name	Pyrrolidine, 1-cinnamoyl-
Synonyms	(2E)-3-Phenyl-1-(1-pyrrolidinyl)-2-propen-1-one Pyrrolidine, 1-cinnamoyl- (2E)-3-phenyl-1-(pyrrolidin-1-yl)prop-2-en-1-one 2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)-

Description	1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
Target	IC50: 37.3 μM (1-Cinnamoylpyrrolidine)[2]
References	[1]. Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9. [2]. Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24.

Hazard Codes	Xi