Cinnamopyrrolidide

Modify Date: 2024-01-04 10:56:44

Cinnamopyrrolidide Structure
Cinnamopyrrolidide structure
Common Name Cinnamopyrrolidide
CAS Number 52438-21-8 Molecular Weight 201.264
Density 1.1±0.1 g/cm3 Boiling Point 386.0±12.0 °C at 760 mmHg
Molecular Formula C13H15NO Melting Point 123℃
MSDS N/A Flash Point 184.4±10.8 °C

 Use of Cinnamopyrrolidide


1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].

 Names

Name Pyrrolidine, 1-cinnamoyl-
Synonym More Synonyms

 Cinnamopyrrolidide Biological Activity

Description 1-Cinnamoylpyrrolidine (Compound 3), a crude extract prepared from Piper caninum, is a DNA strand scission agent, induces the relaxation of supercoiled pBR322 plasmid DNA[1].1-Cinnamoylpyrrolidine (Compound 4) inhibits platelet aggregation induced by PAF with an IC50 of 37.3 μM[2].
Related Catalog
Target

IC50: 37.3 μM (1-Cinnamoylpyrrolidine)[2]

References

[1]. Send toBioorg Med Chem.Ma J, et al. Phenolic acid amides: a new type of DNA strand scission agent from Piper caninum. Bioorg Med Chem. 2004 Jul 15;12(14):3885-9.

[2]. Chen IS, et al. Amides with anti-platelet aggregation activity from Piper taiwanense. Fitoterapia. 2007 Sep;78(6):414-9. Epub 2007 May 24.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 386.0±12.0 °C at 760 mmHg
Melting Point 123℃
Molecular Formula C13H15NO
Molecular Weight 201.264
Flash Point 184.4±10.8 °C
Exact Mass 201.115356
LogP 2.18
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.606

 Safety Information

Hazard Codes Xi

 Synonyms

(2E)-3-Phenyl-1-(1-pyrrolidinyl)-2-propen-1-one
Pyrrolidine, 1-cinnamoyl-
(2E)-3-phenyl-1-(pyrrolidin-1-yl)prop-2-en-1-one
2-Propen-1-one, 3-phenyl-1-(1-pyrrolidinyl)-, (2E)-