1449779-49-0
1449779-49-0 structure
- Name: DGAT1-IN-1
- Chemical Name: {trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid
- CAS Number: 1449779-49-0
- Molecular Formula: C30H28F3N3O4
- Molecular Weight: 551.556
- Catalog: Signaling Pathways Metabolic Enzyme/Protease Acyltransferase
- Create Date: 2018-04-13 00:22:13
- Modify Date: 2024-01-05 15:54:52
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DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value: < 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815.
| Name | {trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid |
|---|---|
| Synonyms |
{trans-4-[4-(2-{[4-(Trifluoromethoxy)benzyl]carbamoyl}imidazo[1,2-a]pyridin-6-yl)phenyl]cyclohexyl}acetic acid
Cyclohexaneacetic acid, 4-[4-[2-[[[[4-(trifluoromethoxy)phenyl]methyl]amino]carbonyl]imidazo[1,2-a]pyridin-6-yl]phenyl]-, trans- DGAT1-IN-1 |
| Description | DGAT1-IN-1 is a potent DGAT1 inhibitor with IC50 of < 10 nM(cell lysate from Hep3B cells overexpressing human DGAT1).IC50 value: < 10 nMTarget: DGAT1 inhibitorImidazopyridine and imidazothiazole compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme and their preparationBy Kim, Dooseop; Bok, Juhan; Shin, Sunmi From PCT Int. Appl. (2013), WO 2013119040 A1 20130815. |
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| Related Catalog | |
| References |
[1]. Compounds as inhibitors of diacylglycerol o-acyltransferase type 1 enzyme , Patent: WO 2013119040 A1 |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C30H28F3N3O4 |
| Molecular Weight | 551.556 |
| Exact Mass | 551.203186 |
| LogP | 6.92 |
| Index of Refraction | 1.620 |
| Storage condition | 2-8℃ |