Name | AZD4205 |
---|
Description | JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1]. |
---|---|
Related Catalog | |
Target |
JAK1:85 nM (IC50) JAK2:12.8 μM (IC50) |
References |
[1]. Annika Birgitta Margareta ÅSTRAND, et al. Compounds and methods for inhibiting jak. |
No Any Chemical & Physical Properties |