JAK1-IN-4

Modify Date: 2024-01-10 09:49:37

JAK1-IN-4 structure	Common Name	JAK1-IN-4
	CAS Number	2091134-35-7	Molecular Weight	N/A
	Density	N/A	Boiling Point	N/A
	Molecular Formula	N/A	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of JAK1-IN-4

JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1].

Name	AZD4205

Description	JAK1-IN-4 is a potent and selective JAK1 inhibitor, with IC50s of 85 nM, 12.8 μM and >30 μM for JAK1, JAK2, and JAK3, respectively. JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK
Target	JAK1:85 nM (IC50) JAK2:12.8 μM (IC50)
References	[1]. Annika Birgitta Margareta ÅSTRAND, et al. Compounds and methods for inhibiting jak.

No Any Chemical & Physical Properties

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: JAK1-IN-4
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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