318480-38-5

318480-38-5 structure

Name: Adrenomedullin (16-31), human
Chemical Name: Adrenomedullin (16-31) (human, pig)
CAS Number: 318480-38-5
Molecular Formula: C₈₂H₁₂₉N₂₅O₂₁S₂
Molecular Weight: 1865.19
Catalog: Signaling Pathways GPCR/G Protein CGRP Receptor
Create Date: 2018-06-26 11:13:07
Modify Date: 2024-01-02 17:49:33
Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor activity in the systemic vascular bed of the rat, but not the cat[1].

Name	Adrenomedullin (16-31) (human, pig)
Synonyms	L-Tyrosinamide, N-[[(4R,7S,13S,16S,19R)-19-amino-16-[3-[(aminoiminomethyl)amino]propyl]-7-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl- N-({(4R,7S,13S,16S,19R)-19-Amino-13-benzyl-16-(3-carbamimidamidopropyl)-7-[(1R)-1-hydroxyethyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}carbonyl)-L-threonyl-L-valyl-L-glutaminyl-L-lysyl-L-leucyl-L-alanyl-L-histidyl-L-glutaminyl-L-isoleucyl-L-tyrosinamide CRFGTCTVQKLAHQIY-NH2(Disulfidebridge1-6)

Description	Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor activity in the systemic vascular bed of the rat, but not the cat[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CGRP Receptor Research Areas >> Cardiovascular Disease Signaling Pathways >> Neuronal Signaling >> CGRP Receptor
References	[1]. Champion HC, et al. Adrenomedullin (16-31) has pressor activity in the rat but not the cat. Peptides. 1997;18(1):133-6.