1363398-67-7
1363398-67-7 structure
- Name: Isophysalin A
- Chemical Name: (1S,2S,3S,5R,6S,7R,14R,15S,18S,21S)-5,7,18-Trihydroxy-1,14,21-trimethyl-25-methylene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone
- CAS Number: 1363398-67-7
- Molecular Formula: C28H30O10
- Molecular Weight: 526.53
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2018-07-20 08:09:01
- Modify Date: 2025-08-25 17:18:06
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Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity[1].
| Name | (1S,2S,3S,5R,6S,7R,14R,15S,18S,21S)-5,7,18-Trihydroxy-1,14,21-trimethyl-25-methylene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone |
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| Synonyms | (1S,2S,3S,5R,6S,7R,14R,15S,18S,21S)-5,7,18-Trihydroxy-1,14,21-trimethyl-25-methylene-4,20,23-trioxaheptacyclo[20.3.1.12,5.03,18.03,21.06,15.09,14]heptacosa-8,10-diene-13,19,24,27-tetrone |
| Description | Isophysalin A is a physalin with alpha and beta unsaturated ketone components. Isophysalin A binds to GSH and targets multiple cysteine residues on IKKβ. Isophysalin A also inhibits inducible NO synthase (iNOS) and nitric oxide (NO) production, showing anti-inflammatory activity[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
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| Boiling Point | 846.6±65.0 °C at 760 mmHg |
| Molecular Formula | C28H30O10 |
| Molecular Weight | 526.53 |
| Flash Point | 286.6±27.8 °C |
| Exact Mass | 526.183899 |
| LogP | 2.60 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.669 |
| Hazard Codes | Xi |
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