1402438-74-7
1402438-74-7 structure
- Name: PF 06273340
- Chemical Name: I136775ABW
- CAS Number: 1402438-74-7
- Molecular Formula: C23H22ClN7O3
- Molecular Weight: 479.919
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Trk Receptor
- Create Date: 2018-06-12 17:01:01
- Modify Date: 2025-08-25 11:10:01
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PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1].
| Name | I136775ABW |
|---|---|
| Synonyms |
PF-06273340
2-Pyridineacetamide, N-[5-[[2-amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro- N-(5-{[2-Amino-7-(1-hydroxy-2-methyl-2-propanyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl}-3-pyridinyl)-2-(5-chloro-2-pyridinyl)acetamide I136775ABW |
| Description | PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1]. |
|---|---|
| Related Catalog | |
| Target |
TRK |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C23H22ClN7O3 |
| Molecular Weight | 479.919 |
| Exact Mass | 479.147278 |
| LogP | 0.92 |
| Index of Refraction | 1.711 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| RIDADR | NONH for all modes of transport |