14705-60-3
14705-60-3 structure
- Name: Cyclo(Phe-Pro)
- Chemical Name: cyclo(phenylalanyl-prolyl)
- CAS Number: 14705-60-3
- Molecular Formula: C14H16N2O2
- Molecular Weight: 244.289
- Catalog: Research Areas Infection
- Create Date: 2018-06-30 22:33:26
- Modify Date: 2025-08-25 11:37:25
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Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)), a Vibrio vulnificus quorum-sensing molecule, inhibits retinoic acid-inducible gene-I (RIG-I) polyubiquitination, through its specific interaction with RIG-I, to blunt IRF-3 activation and type-I IFN production. Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) enhances susceptibility to hepatitis C virus (HCV), as well as Sendai and influenza viruses[1].
| Name | cyclo(phenylalanyl-prolyl) |
|---|---|
| Synonyms |
3-Benzyl-hexahydro-pyrrolo[1,2-a]pyrazine-1,4-dione
3-Benzylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(phenylmethyl)- cyclo(phenylalanyl-prolyl) |
| Description | Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)), a Vibrio vulnificus quorum-sensing molecule, inhibits retinoic acid-inducible gene-I (RIG-I) polyubiquitination, through its specific interaction with RIG-I, to blunt IRF-3 activation and type-I IFN production. Cyclo(Phe-Pro) (Cyclo(phenylalanylprolyl)) enhances susceptibility to hepatitis C virus (HCV), as well as Sendai and influenza viruses[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 509.5±39.0 °C at 760 mmHg |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.289 |
| Flash Point | 262.0±27.1 °C |
| Exact Mass | 244.121185 |
| LogP | -0.56 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.614 |