161314-17-6

161314-17-6 structure

Name: NNGH
Chemical Name: N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
CAS Number: 161314-17-6
Molecular Formula: C₁₃H₂₀N₂O₅S
Molecular Weight: 316.373
Catalog: Signaling Pathways Metabolic Enzyme/Protease MMP
Create Date: 2018-07-08 01:30:09
Modify Date: 2024-01-13 20:02:06
NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression[1].

Name	N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
Synonyms	Acetamide, N-hydroxy-2-[[(4-methoxyphenyl)sulfonyl](2-methylpropyl)amino]- N-Hydroxy-N2-isobutyl-N2-[(4-methoxyphenyl)sulfonyl]glycinamide N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID

Description	NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
References	[1]. Laurence Blavier, et al. Stromelysin-1 (MMP-3) is a target and a regulator of Wnt1-induced epithelial-mesenchymal transition (EMT). Cancer Biol Ther. 2010 Jul 15;10(2):198-208.

RIDADR	NONH for all modes of transport