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23532-11-8

23532-11-8 structure
23532-11-8 structure
  • Name: 8-debenzoylpaeoniflorin
  • Chemical Name: (1R,2S,3R,5R,6R,8S)-6-Hydroxy-2-(hydroxymethyl)-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]dec-3-yl β-D-glucopyranoside
  • CAS Number: 23532-11-8
  • Molecular Formula: C16H24O10
  • Molecular Weight: 376.356
  • Catalog: Natural product Moss
  • Create Date: 2018-07-07 14:23:11
  • Modify Date: 2024-01-13 21:20:01
  • 8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity[1].

Name (1R,2S,3R,5R,6R,8S)-6-Hydroxy-2-(hydroxymethyl)-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]dec-3-yl β-D-glucopyranoside
Synonyms β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS)-tetrahydro-5-hydroxy-5b-(hydroxymethyl)-2-methyl-2,5-methano-1H-3,4-dioxacyclobuta[cd]pentalen-1a(2H)-yl
(1R,2S,3R,5R,6R,8S)-6-Hydroxy-2-(hydroxymethyl)-8-methyl-9,10-dioxatetracyclo[4.3.1.02,5.03,8]dec-3-yl β-D-glucopyranoside
Description 8-Debenzoylpaeoniflorin, a monoterpene glycoside, is a natural product that could be isolated from the dried root of Paeonia lactiflora Pall. 8-Debenzoylpaeoniflorin has antihyperglycemic activity[1].
Related Catalog
In Vivo 8-Debenzoylpaeoniflorin (1-10 mg/kg; i.v.; 单次注射) 具有抗高血糖活性,并降低 stz-糖尿病大鼠的血糖水平[1]。 Animal Model: Male Wistar STZ-diabetic rats (210-250g)[1] Dosage: 1, 5, and 10 mg/kg Administration: Intravenous injection, single dose Result: Decreased plasma glucose levels in a time- and dose-dependent manner in STZ-diabetic rats.
References

[1]. Hsu FL, et, al. Antihyperglycemic effects of paeoniflorin and 8-debenzoylpaeoniflorin, glucosides from the root of Paeonia lactiflora. Planta Med. 1997 Aug;63(4):323-5.  

Density 1.8±0.1 g/cm3
Boiling Point 626.9±55.0 °C at 760 mmHg
Molecular Formula C16H24O10
Molecular Weight 376.356
Flash Point 332.9±31.5 °C
Exact Mass 376.136932
LogP -2.64
Vapour Pressure 0.0±4.2 mmHg at 25°C
Index of Refraction 1.695
Hazard Codes Xi