Name | {4-[(Carbamimidoylsulfanyl)methyl]phenyl}boronic acid hydrobromide (1:1) |
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Synonyms |
{4-[(Carbamimidoylsulfanyl)methyl]phenyl}boronic acid hydrobromide (1:1)
Carbamimidothioic acid, (4-boronophenyl)methyl ester, hydrobromide (1:1) |
Description | BC-11 hydrobromide is a selective TMPRSS2 inhibitor (TMPRSS2 is a key host cellular factor for viral entry and SARS-CoV-2 pathogenesis), and a selective urokinase (uPA) inhibitor (IC50=8.2 μM). BC-11 hydrobromide is cytotoxic to triple-negative MDA-MB231 breast cancer cells. BC-11 hydrobromide is used in research on viral infections and cancer[1][2][3]. |
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Related Catalog | |
Target |
IC50: 8.2 μM (uPA)[3]. |
References |
Molecular Formula | C8H12BBrN2O2S |
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Molecular Weight | 290.97 |
Exact Mass | 289.989594 |