1319738-39-0
1319738-39-0 structure
- Name: BI1002494
- Chemical Name: (4R)-4-[(1R)-1-{[7-(3,4,5-Trimethoxyphenyl)-1,6-naphthyridin-5-yl]oxy}ethyl]-2-pyrrolidinone
- CAS Number: 1319738-39-0
- Molecular Formula: C23H25N3O5
- Molecular Weight: 423.462
- Create Date: 2018-07-04 23:14:24
- Modify Date: 2024-02-24 16:36:44
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BI1002494 (BI-1002494) is a novel, potent, and selective spleen tyrosine kinase (SYK) inhibitor with enzyme IC50 of 30 nM, cell IC50 of 7 nM (FcεR1-mediated histamine release in human monocyte-derived mast cells, in the presence of 0.1% albumin).
| Name | (4R)-4-[(1R)-1-{[7-(3,4,5-Trimethoxyphenyl)-1,6-naphthyridin-5-yl]oxy}ethyl]-2-pyrrolidinone |
|---|---|
| Synonyms |
(4R)-4-[(1R)-1-{[7-(3,4,5-Trimethoxyphenyl)-1,6-naphthyridin-5-yl]oxy}ethyl]-2-pyrrolidinone
2-Pyrrolidinone, 4-[(1R)-1-[[7-(3,4,5-trimethoxyphenyl)-1,6-naphthyridin-5-yl]oxy]ethyl]-, (4R)- |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 609.6±55.0 °C at 760 mmHg |
| Molecular Formula | C23H25N3O5 |
| Molecular Weight | 423.462 |
| Flash Point | 322.5±31.5 °C |
| Exact Mass | 423.179413 |
| LogP | 0.95 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.592 |