1449390-12-8
1449390-12-8 structure
- Name: m-PEG6-NHS ester
- Chemical Name: 1-[(20-Oxo-2,5,8,11,14,17-hexaoxaicosan-20-yl)oxy]-2,5-pyrrolidinedione
- CAS Number: 1449390-12-8
- Molecular Formula: C18H31NO10
- Molecular Weight: 421.439
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2018-06-03 19:08:55
- Modify Date: 2025-08-25 19:29:29
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m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
| Name | 1-[(20-Oxo-2,5,8,11,14,17-hexaoxaicosan-20-yl)oxy]-2,5-pyrrolidinedione |
|---|---|
| Synonyms |
1-[(20-Oxo-2,5,8,11,14,17-hexaoxaicosan-20-yl)oxy]-2,5-pyrrolidinedione
2,5-Pyrrolidinedione, 1-[(1-oxo-4,7,10,13,16,19-hexaoxaeicos-1-yl)oxy]- mPEG5-NHS |
| Description | m-PEG6-NHS ester is a non-cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 502.6±60.0 °C at 760 mmHg |
| Molecular Formula | C18H31NO10 |
| Molecular Weight | 421.439 |
| Flash Point | 257.8±32.9 °C |
| Exact Mass | 421.194794 |
| LogP | -3.59 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.489 |
| Hazard Codes | Xi |
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