303215-67-0
303215-67-0 structure
- Name: MitoBloCK-6
- Chemical Name: 2-{(E)-[(4-Anilinophenyl)imino]methyl}-4,6-dichlorophenol
- CAS Number: 303215-67-0
- Molecular Formula: C19H14Cl2N2O
- Molecular Weight: 357.233
- Catalog: Signaling Pathways Apoptosis Apoptosis
- Create Date: 2018-07-12 12:36:31
- Modify Date: 2024-01-11 06:36:22
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MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1].
| Name | 2-{(E)-[(4-Anilinophenyl)imino]methyl}-4,6-dichlorophenol |
|---|---|
| Synonyms |
2-{(E)-[(4-Anilinophenyl)imino]methyl}-4,6-dichlorophenol
2,4-Dichloro-6-[(4-phenylamino-phenylimino)-methyl]-phenol MFCD00557142 Phenol, 2,4-dichloro-6-[(E)-[[4-(phenylamino)phenyl]imino]methyl]- |
| Description | MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 900 nM (Erv1) 700 nM (ALR) 1.4 μM (Erv2)[1] |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 535.1±50.0 °C at 760 mmHg |
| Molecular Formula | C19H14Cl2N2O |
| Molecular Weight | 357.233 |
| Flash Point | 277.4±30.1 °C |
| Exact Mass | 356.048309 |
| LogP | 6.34 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.627 |